KRT20
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Official Full Name
Keratin 20
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Background
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. -
Synonyms
K20; CD20; CK20; CK-20; KRT21; MGC35423; KRT20; keratin, type I cytoskeletal 20; keratin-20; protein IT; cytokeratin 20; cytokeratin-20; OTTHUMP00000164518;
- Involved Pathway
- Protein Function
- Interacting Protein
KRT20 involved in several pathways and played different roles in them. We selected most pathways KRT20 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
KRT20 has several biochemical functions, for example, protein binding, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT20 itself. We selected most functions KRT20 had, and list some proteins which have the same functions with KRT20. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | VAT1L;KRTAP9-2;HADHB;TOM1L1;ZNF434;MYO7B;CENPI;GLIS2;SH2D3A |
| structural constituent of cytoskeleton | SPTBN1;KRT15;TUBA8;TUBA2;COX4I2;TUBA8L;INA;MAPT;CCDC6 |
KRT20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT20 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT20.
C9orf16; VIM; KRT15; TFIP11; KRT13
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