KRT80
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Official Full Name
keratin 80 -
Overview
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This genes expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene. -
Synonyms
KRT80;keratin 80;keratin, type II cytoskeletal 80;KB20;K80;CK-80;keratin-80;keratin b20;cytokeratin-80;type II keratin;type-II keratin Kb20
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KRT80-471H | Recombinant Human KRT80 protein, His-tagged | E.coli | Human | His | 1-422 aa | |
| KRT80-3333R | Recombinant Rat KRT80 Protein | Mammalian Cells | Rat | His |
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| KRT80-8856M | Recombinant Mouse KRT80 Protein | Mammalian Cells | Mouse | His |
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| KRT80-2989R | Recombinant Rat KRT80 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| KRT80-2989R-B | Recombinant Rat KRT80 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| KRT80-4942M | Recombinant Mouse KRT80 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| KRT80-4942M-B | Recombinant Mouse KRT80 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
KRT80 involved in several pathways and played different roles in them. We selected most pathways KRT80 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT80 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KRT80 has several biochemical functions, for example, protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT80 itself. We selected most functions KRT80 had, and list some proteins which have the same functions with KRT80. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | KRT76,CLDN11A,MAP7,CLDN18,FGA,CRYBB2,KRT93,MTAP7D3,FLG,NEFMA |
| protein binding | TYK2,C2orf62,FBP1,TNNI3K,JMY,SNCA,ARR3,CLPB,HPSE,RAD50 |
Interacting Protein
KRT80 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT80 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT80.
MEOX2;KRT15;KRT20;midostaurin;GABARAPL2
Resources
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References
- Shum, WW; Smith, TB; et al. Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis. BIOLOGY OF REPRODUCTION 90:-(2014).
- Grobe, A; Blessmann, M; et al. Prognostic Relevance of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow of Patients with Squamous Cell Carcinoma of the Oral Cavity. CLINICAL CANCER RESEARCH 20:425-433(2014).
