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LETMD1

Official Full Name

LETM1 domain containing 1
Overview

This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene.
Synonyms

LETMD1; LETM1 domain containing 1; LETM1 domain-containing protein 1; cervical cancer 1 protooncogene; HCCR1; 1110019O13Rik; Cervical cancer 1 proto oncogene protein; Cervical cancer proto oncogene 2 protein; DKFZp586A011; HCCR 2; HCCR2; HCRR 2; HCRR2; Regulator of TP53; cervical cancer proto-oncogene 2 protein; cervical cancer 1 proto-oncogene protein p40; HCCR-1; HCCR-2; HCRR-2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Bos taurus (Bovine)
Human
Mouse

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LETMD1-29425TH	Recombinant Human LETMD1, His-tagged	E.coli	His		Inquiry
Human	LETMD1-4771HCL	Recombinant Human LETMD1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	LETMD1-4175H	Recombinant Human LETMD1 Protein (Pro162-Asn347), N-His tagged	E.coli	N-His	Pro162-Asn347	Inquiry
Mouse	LETMD1-9058M	Recombinant Mouse LETMD1 Protein	Mammalian Cell	His		Inquiry
Mouse	LETMD1-5051M-B	Recombinant Mouse LETMD1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	LETMD1-5051M	Recombinant Mouse LETMD1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Bos taurus (Bovine)	RFL15547BF	Recombinant Full Length Bovine Letm1 Domain-Containing Protein 1(Letmd1) Protein, His-Tagged	E.coli expression system	His	Full Length (1-360)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
LETMD1 Related Articles

LETMD1 involved in several pathways and played different roles in them. We selected most pathways LETMD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LETMD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

LETMD1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LETMD1 itself. We selected most functions LETMD1 had, and list some proteins which have the same functions with LETMD1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	CRHBP;UBTD1;USP10;CCND2;MAST2;C3;MIF4GD;OLIG3;CDK1

LETMD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LETMD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LETMD1.

REEP5; SH2D1A; HCK; RAB5C; Rab5b; Ypel5; NCBP1; Cdc37; Gpsm1; Anapc2; Cenpq; Ormdl2; Cxxc1; Tsc1; JRKL

Schlickum, S; Moghekar, A; et al. LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein. GENOMICS 83:254-261(2004).