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LHX2

Official Full Name

LIM homeobox 2
Overview

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique;cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can;recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function;during evolution.
Synonyms

LHX2; LIM homeobox 2; LIM/homeobox protein Lhx2; hLhx2; LH 2; Homeobox protein LH2; Human LIM homeobox domain protein (hLH 2) mRNA complete cds; LH2; LIM HOX gene 2; LIM protein Lhx2; OTTHUMP00000022092; OTTHUMP00000022093; homeobox protein LH-2; LIM homeobox protein 2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LHX2-660H	Recombinant Human LHX2	Mammalian Cell	His		Inquiry
Human	LHX2-569H	Recombinant Human LHX2, His-tagged	E.coli	His	1-396aa	$319 / 25ug
Human	LHX2-45H	Recombinant Human LHX2 protein, His-tagged	E.coli	His		Inquiry
Human	LHX2-4751HCL	Recombinant Human LHX2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	LHX2-3356H-B	Recombinant Human LHX2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	LHX2-3356H	Recombinant Human LHX2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	LHX2-2509R	Recombinant Rhesus monkey LHX2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	LHX2-2330R	Recombinant Rhesus Macaque LHX2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	LHX2-2330R-B	Recombinant Rhesus Macaque LHX2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	LHX2-6452C	Recombinant Chicken LHX2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

LHX2 involved in several pathways and played different roles in them. We selected most pathways LHX2 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LHX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neural Crest Differentiation	DMBX1;ZIC1;TXLNB;CDH6;CDH7;MBP;DLX5;PMP22;OLIG1

LHX2 has several biochemical functions, for example, chromatin binding, sequence-specific DNA binding, transcription factor activity, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LHX2 itself. We selected most functions LHX2 had, and list some proteins which have the same functions with LHX2. You can find most of the proteins on our site.

Function	Related Protein
chromatin binding	GLI1;PLAC8;ATXN7;YBX1;TCF7L2;TLE4;RBMX;SOD3;TGIF1
sequence-specific DNA binding	MEOX2;NFIL3-2;VSX1;FOXC1A;NKX2.3;CREB3L3A;HOXB8A;ETV5A;PBX2
transcription factor activity, RNA polymerase II transcription factor binding	SRF;THRAA;MYOCD;MAMSTR;ATF2;LHX2;HIF1A;YAP1;ATF4
zinc ion binding	ZCCHC13;RFPL4B;ZMYM2;RPH3A;SH3RF1;RARGB;RSPRY1;ZDHHC3A;DTX3L

LHX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LHX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LHX2.