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LIMS2

Official Full Name

LIM and senescent cell antigen-like domains 2
Overview

LIMS2 is a focal adhesion protein that associates with integrin-linked kinase (ILK; MIM 602366), a multidomain protein that mediates multiple protein-protein interactions at adhesion sites between cells and the extracellular matrix (ECM).
Synonyms

LIMS2; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; FLJ10044; LIM-like protein 2; LIMS2_HUMAN; Particularly interesting new Cys-His protein 2; PINCH-2; ILK-binding protein; PINCH2;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Mouse
Rhesus Macaque
Zebrafish

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	LIMS2-9111M	Recombinant Mouse LIMS2 Protein	Mammalian Cell	His	Inquiry
Mouse	LIMS2-5088M	Recombinant Mouse LIMS2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	LIMS2-5088M-B	Recombinant Mouse LIMS2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	LIMS2-2520R	Recombinant Rhesus monkey LIMS2 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	LIMS2-2340R	Recombinant Rhesus Macaque LIMS2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	LIMS2-2340R-B	Recombinant Rhesus Macaque LIMS2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	LIMS2-2836Z	Recombinant Zebrafish LIMS2	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
LIMS2 Related Articles

LIMS2 involved in several pathways and played different roles in them. We selected most pathways LIMS2 participated on our site, such as PodNet: protein-protein interactions in the podocyte, XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with LIMS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
PodNet: protein-protein interactions in the podocyte	DDN;FAM65A;LIMS2;SDK1;TENC1;CMIP;FRAS1
XPodNet - protein-protein interactions in the podocyte expanded by STRING	FAM65A;FRAS1;ATP9A;SDK1;GAB3;GMCL1;CLNK;GIMAP3;LIMS2

LIMS2 has several biochemical functions, for example, metal ion binding, molecular_function, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LIMS2 itself. We selected most functions LIMS2 had, and list some proteins which have the same functions with LIMS2. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	STK24;MEP1A.1;KAT8;THAP3;PARP12;SMYD1A;REV3L;MOBKL2A;RNF44
molecular_function	GLT25D2;GSDMC;DEFB37;GM9524;MXRA8A;MAGEA12;SHISA9B;SMU1A;TMEM41AA
zinc ion binding	RFWD3;RNF146;TRIM28;TRIM71;LIMK2;TOP3A;CAPNS2;YY1;LNX2B

LIMS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIMS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LIMS2.

Uribe, V; Badia-Careaga, C; et al. Arid3b is essential for second heart field cell deployment and heart patterning. DEVELOPMENT 141:4168-4181(2014).

Haam, K; Kim, HJ; et al. Epigenetic silencing of BTB and CNC homology 2 and concerted promoter CpG methylation in gastric cancer. CANCER LETTERS 351:206-214(2014).