lims2

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lims2

Official Full Name LIM and senescent cell antigen-like domains 2
Background LIMS2 is a focal adhesion protein that associates with integrin-linked kinase (ILK; MIM 602366), a multidomain protein that mediates multiple protein-protein interactions at adhesion sites between cells and the extracellular matrix (ECM).
Synonyms LIMS2; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; FLJ10044; LIM-like protein 2; LIMS2_HUMAN; Particularly interesting new Cys-His protein 2; PINCH-2; ILK-binding protein; PINCH2
    • Species :
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse LIMS2-9111M Recombinant Mouse LIMS2 Protein Mammalian Cell His
    Rhesus Macaque LIMS2-2520R Recombinant Rhesus monkey LIMS2 Protein, His-tagged Mammalian Cell His
    Zebrafish LIMS2-2836Z Recombinant Zebrafish LIMS2 Mammalian Cell His

    lims2 involved in several pathways and played different roles in them. We selected most pathways lims2 participated on our site, such as PodNet: protein-protein interactions in the podocyte, XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with lims2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PodNet: protein-protein interactions in the podocyte FRAS1; TENC1; SDK1; CMIP; FAM65A; LIMS2; DDN
    XPodNet - protein-protein interactions in the podocyte expanded by STRING OASL2; ARHGAP33; WLS; MICALL2; PKD1; GJB6; FLII; SNTB1; SDK1; CDC42EP5

    lims2 has several biochemical functions, for example, metal ion binding, molecular_function, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by lims2 itself. We selected most functions lims2 had, and list some proteins which have the same functions with lims2. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding MT2; SIRT1; ZFP536; ADH8A; GMIP; CNOT8; SCNM1; FTR82; ITGA2; BMPR1B
    molecular_function SAMM50L; LRIT1; MYADML2; FER1L4; TAGAP1; DNAJB13; DEFB19; NIPAL2; FAM210B; MRGPRA5
    zinc ion binding MAN2B2; SKI; TRIM62; Car8; ZNRF2A; USP45; MBD1; GDA; ZFAND5; HIF1AN

    lims2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with lims2 here. Most of them are supplied by our site. Hope this information will be useful for your research of lims2.

    Uribe, V; Badia-Careaga, C; et al. Arid3b is essential for second heart field cell deployment and heart patterning. DEVELOPMENT 141:4168-4181(2014).
    Haam, K; Kim, HJ; et al. Epigenetic silencing of BTB and CNC homology 2 and concerted promoter CpG methylation in gastric cancer. CANCER LETTERS 351:206-214(2014).

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