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LPCAT1

  • Official Full Name

    lysophosphatidylcholine acyltransferase 1

  • Overview

    Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to;phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006 (PubMed;16704971)).
  • Synonyms

    LPCAT1; lysophosphatidylcholine acyltransferase 1; acyltransferase like 2 , AYTL2; FLJ12443; LPCAT-1; lysoPAFAT; LPC acyltransferase 1; acyltransferase like 2; acyltransferase-like 2; lysoPC acyltransferase 1; lyso-PAF acetyltransferase; regulated by phos;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LPCAT1-7568H Recombinant Human LPCAT1, His-tagged E.coli His 79-534aa
Human LPCAT1-620H Recombinant Human LPCAT1, GST-tagged E.coli GST C-term-345aa
Human LPCAT1-4672HCL Recombinant Human LPCAT1 293 Cell Lysate HEK293 N/A
Human LPCAT1-516H Recombinant Human LPCAT1 Protein, His-tagged E.coli His Pro70~Arg237
Human LPCAT1-2015H Recombinant Human LPCAT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse LPCAT1-9195M Recombinant Mouse LPCAT1 Protein Mammalian Cell His
Mouse LPCAT1-5137M-B Recombinant Mouse LPCAT1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Lpcat1-1793M Recombinant Mouse Lpcat1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Lpcat1-517M Recombinant Mouse Lpcat1 Protein, His/GST-tagged E.coli His/GST Ala301~Cys514
Mouse LPCAT1-5137M Recombinant Mouse LPCAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LPCAT1-3437R Recombinant Rat LPCAT1 Protein Mammalian Cell His
Rat LPCAT1-3093R Recombinant Rat LPCAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LPCAT1-3093R-B Recombinant Rat LPCAT1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LPCAT1-3880Z Recombinant Zebrafish LPCAT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LPCAT1 Related Articles

LPCAT1 involved in several pathways and played different roles in them. We selected most pathways LPCAT1 participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPCAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerophospholipid metabolismPLA2G4D;EPT1;PLA2G5;GPAM;PLB1;CHAT;TAE1;MBOAT7;PPAP2C
Ether lipid metabolismPLB1;PPAP2C;LPCAT2;ENPP2;PAFAH1B1A;PLA2G16;PLA2G2E;PLD1;PLA2G5
Metabolic pathwaysGBGT1L4;HKDC1;GCLM;HSD17B12B;NSDHL;ACSM2;HSD17B12A;KHK;DAK

LPCAT1 has several biochemical functions, for example, 1-acylglycerophosphocholine O-acyltransferase activity, 1-alkenylglycerophosphocholine O-acyltransferase activity, 1-alkylglycerophosphocholine O-acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LPCAT1 itself. We selected most functions LPCAT1 had, and list some proteins which have the same functions with LPCAT1. You can find most of the proteins on our site.

Function Related Protein
1-acylglycerophosphocholine O-acyltransferase activityLPCAT2;TAZ;LPCAT3;LPCAT4;LPCAT1
1-alkenylglycerophosphocholine O-acyltransferase activity
1-alkylglycerophosphocholine O-acetyltransferase activityLPCAT4;LPCAT1;LPCAT2
1-alkylglycerophosphocholine O-acyltransferase activity
calcium ion bindingFLG2;CAPN2;EFCAB5;LOC100686744;GUCA1A;PLCB1;TPT1;CALM3;C1R

LPCAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPCAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LPCAT1.

ESR1; ILK; Sap25; HIPK4

Mansilla, F; da Costa, KA; et al. Lysophosphatidylcholine acyltransferase 1 (LPCAT1) overexpression in human colorectal cancer. JOURNAL OF MOLECULAR MEDICINE-JMM 87:85-97(2009).
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