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LRRK1

  • Official Full Name

    leucine-rich repeat kinase 1

  • Overview

    Leucine-rich repeat serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the LRRK1 gene.
  • Synonyms

    LRRK1; leucine-rich repeat kinase 1; leucine-rich repeat serine/threonine-protein kinase 1; FLJ23119; KIAA1790; RIPK6; Roco1; Leucine rich repeat serine/threonine protein kinase 1; LRRK 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LRRK1-647H Recombinant Human LRRK1, His-tagged E.coli His C-term-357aa
Human LRRK1-1035HCL Recombinant Human LRRK1 cell lysate N/A
Human LRRK1-6078HF Recombinant Full Length Human LRRK1 Protein, GST-tagged In Vitro Cell Free System GST 261 amino acids
Human LRRK1-4638H Recombinant Human LRRK1 Protein, GST-tagged Wheat Germ GST
Mouse LRRK1-9309M Recombinant Mouse LRRK1 Protein Mammalian Cell His
Mouse LRRK1-5212M-B Recombinant Mouse LRRK1 Protein Pre-coupled Magnetic Beads HEK293
Mouse LRRK1-5212M Recombinant Mouse LRRK1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LRRK1 Related Articles

LRRK1 involved in several pathways and played different roles in them. We selected most pathways LRRK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LRRK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

LRRK1 has several biochemical functions, for example, ATP binding, GTP binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRRK1 itself. We selected most functions LRRK1 had, and list some proteins which have the same functions with LRRK1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTRIP13;CLK2B;CKMT2;AKT3;ASS1;NVL;MTHFD1L;HELZ2;BAZ1B
GTP bindingARL11;EIF2B2;INSR;SEPT8B;RAC1B;GTPBP2;RRAGD;RHOT1A;RAB26
identical protein bindingSNX33;DYNLT1F;EWSR1;NDE1;CDC42BPA;PON2;SNX1;CAV1;TP73
metal ion bindingGLIS3;POLD1;SIAH2L;ESYT1;MUSK;ING5B;ZKSCAN4;NUDT15;CYB561
protein bindingROR2;NQO2;MDH1;H2-KE2;HYLS1;ZCCHC10;GRASP;NEDD8;LTBR
protein serine/threonine kinase activityIRAK4;PAK2;CDK15;RPS6KC1;BMPR1AA;CAMK1GB;PRKDC;RPS6KA1;STK32C

LRRK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRRK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRRK1.

BAG5; ABL1; LRRK2; EGFR; HSPA8; GRB2

Biskup, S; Moore, DJ; et al. Dynamic and redundant regulation of LRRK2 and LRRK1 expression. BMC NEUROSCIENCE 8:-(2007).
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