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LTN1

  • Official Full Name

    listerin E3 ubiquitin protein ligase 1

  • Overview

    Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 (PubMed 19196968)).
  • Synonyms

    LTN1; listerin E3 ubiquitin protein ligase 1; C21orf10, C21orf98, chromosome 21 open reading frame 98 , ring finger protein 160 , RNF160, zinc finger protein 294 , ZNF294; E3 ubiquitin-protein ligase listerin; FLJ11053; KIAA0714; LISTERIN; ri;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse LTN1-9355M Recombinant Mouse LTN1 Protein Mammalian Cell His
Mouse LTN1-5241M Recombinant Mouse LTN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse LTN1-5241M-B Recombinant Mouse LTN1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

LTN1 involved in several pathways and played different roles in them. We selected most pathways LTN1 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemCD300LB;ARIH2;ASB14;KIF3C;LAIR1;SIGLEC5;NA;SPSB2;ASB8
Antigen processing: Ubiquitination &ampPJA2;SPSB1;TPP2;RNF138;SPSB4;RNF111;FBXO27;ATG7;ASB10
Proteasome degradationBLMH;KLHL21;RBCK1;CMTM2A;ASB7;STUB1;ASB2;GAN;RNF138
Class I MHC mediated antigen processing &ampNPEPPS;ASB10;SEC24A;LRRC41;CTSL1;ASB17;MKRN1;RNF182;RNF4
presentationNPEPPS;ARIH2;CMTM2A;RNF41;WSB1;STUB1;ASB13;SPSB4;KLHL20
Immune SystemTAX1BP1;MGC174152;Siglece;SUGT1;TREML2;B2ML;POLR3F;CTSE;LGALS9

LTN1 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTN1 itself. We selected most functions LTN1 had, and list some proteins which have the same functions with LTN1. You can find most of the proteins on our site.

Function Related Protein
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activityRNF149;ARIH1L;MGRN1A;TRIM41;MARCH11;MARCH4;NEURL3;MARCH5L;TRIM71
coenzyme F420-0 gamma-glutamyl ligase activityTMEM129;MUL1A;ARIH1L;UBE2IB;TRIM41;RNF144AB;RNF169;RNF149;NEURL1B
coenzyme F420-2 alpha-glutamyl ligase activityLTN1;TRIM50;NEURL3;MARCH9;SIAH1A;NEURL1B;ITCHA;ARIH1L;MARCH5L
ligase activityARIH1;MARCH11;HECW2;TRIM39;ITCHA;RNF212;HERC5;ZNRF2;TRIM38
metal ion bindingZFP637;ZNF572;ZNF443;ZFP41;ZFYVE9;TRIM35-22;NGB;DEAF1;PITPNM1
protein-glutamic acid ligase activityZNRF3;TRIM71;G2E3;MYLIPA;NEURL1B;RNF180;HECW2;SIAH2L;SIAH1A
protein-glycine ligase activityHECW2;RAG1;RNF144AB;RNF169;MUL1A;RNF187;MYLIPB;MYLIPA;TRIM41
protein-glycine ligase activity, elongatingTRIM41;ITCHA;LTN1;NEURL3;UBR1;ARIH1L;TRIM71;SIAH2L;UBE2IA
protein-glycine ligase activity, initiatingG2E3;RC3H2;MUL1A;MGRN1A;LTN1;MARCH6;RFWD2;TMEM129;RNF144AA
ribosomal S6-glutamic acid ligase activityRNF149;RAG1;MARCH4;MUL1A;RFWD2;UBR1;ZNRF2B;NEURL1B;RC3H2
tubulin-glutamic acid ligase activityRNF180;ARIH1L;MARCH5L;NEURL1B;SIAH2L;MYLIPB;RNF187;MUL1A;TRIM41
tubulin-glycine ligase activityZNRF2B;LTN1;TRIM50;SIAH2L;MARCH4;MARCH6;UBE2IB;MUL1A;ARIH1L
ubiquitin protein ligase activityTRAF6;RNF181;CDC42;MED20;RNF144AB;SMURF1;MED17;RNF2;UBE2S
ubiquitin-protein transferase activityMKRN1;UBE2H;PDZRN3B;FANCL;UBE2L6;FBXO7;WWP2;ANKIB1;STUB1
zinc ion bindingCXXC1A;TAB2;UHRF2;RC3H2;Shh;LHX2B;SIRT6;LHX4;CRIP1

LTN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LTN1.

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