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MAGEA5

Official Full Name

melanoma antigen family A, 5
Overview

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene.
Synonyms

MAGEA5; melanoma antigen family A, 5; MAGE5; melanoma-associated antigen 5; cancer/testis antigen family 1; member 5; CT1.5; MAGE 5a antigen; MAGE 5b antigen; MGC129526; Cancer/testis antigen 1.5; Cancer/testis antigen family 1 member 5; MAGE 5 antigen; MAGEA4; Melanoma antigen family A 5; Melanoma associated antigen 5; MAGE-5 antigen; MAGE-5a antigen; MAGE-5b antigen; cancer/testis antigen family 1, member 5;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MAGEA5-4552HCL	Recombinant Human MAGEA5 293 Cell Lysate	HEK293	N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MAGEA5 Related Articles

MAGEA5 involved in several pathways and played different roles in them. We selected most pathways MAGEA5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MAGEA5 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA5 itself. We selected most functions MAGEA5 had, and list some proteins which have the same functions with MAGEA5. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	CRYGM5;LEMD2;CAX1;ASB12B;SINUP;EPHX3;STOML3A;TRAPPC13;KRT24

MAGEA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA5.

Uzdensky, A; Demyanenko, S; et al. Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin. TUMOR BIOLOGY 35:8225-8233(2014).

Chen, YC; Hsu, WL; et al. Expression of MAGE-A restricted to testis and ovary or to various cancers in dogs. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 153:26-34(2013).