MAP1B

  • Official Full Name

    microtubule-associated protein 1B

  • Overview

    This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are;thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene;is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain;and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important;role in development and function of the nervous system.
  • Synonyms

    MAP1B; microtubule-associated protein 1B; MAP5; MAP-1B; FUTSCH; FLJ38954; DKFZp686E1099; DKFZp686F1345;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MAP1B-283H Recombinant Human MAP1B Mammalian Cell His
Human MAP1B-8189H Recombinant Human MAP1B protein, His & T7-tagged E.coli His/T7 Asp2207~Leu2468 (Accession # P46821)
Human MAP1B-30119H Recombinant Human MAP1B protein, GST-tagged E.coli GST Asp414-Lys567
Human MAP1B-4492H Recombinant Human MAP1B Protein (Lys414-Glu567), N-His tagged E.coli N-His Lys414-Glu567
Human MAP1B-3807H Recombinant Human MAP1B protein, His-tagged E.coli His 414-567 aa
Human MAP1B-3428H-B Recombinant Human MAP1B Protein Pre-coupled Magnetic Beads HEK293
Human MAP1B-3428H Recombinant Human MAP1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Map1b-8190M Recombinant Mouse Map1b protein, His & T7-tagged E.coli His/T7 Asp2203~Leu2464 (Accession # P14873)
Rat MAP1B-3556R Recombinant Rat MAP1B Protein Mammalian Cell His
Rat MAP1B-3212R Recombinant Rat MAP1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MAP1B-3212R-B Recombinant Rat MAP1B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MAP1B-2659R Recombinant Rhesus monkey MAP1B Protein, His-tagged Mammalian Cell His
Rhesus Macaque MAP1B-2479R Recombinant Rhesus Macaque MAP1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MAP1B-2479R-B Recombinant Rhesus Macaque MAP1B Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MAP1B involved in several pathways and played different roles in them. We selected most pathways MAP1B participated on our site, such as Lissencephaly gene (LIS1) in neuronal migration and development, Reelin signaling pathway, Regulation of Microtubule Cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Lissencephaly gene (LIS1) in neuronal migration and developmentNDEL1;MAP1B;VLDLR;DAB1;KATNA1;NUDC;DCX;LRPAP1;DYNLT1
Reelin signaling pathwayDAB1;VLDLR;LRPAP1;MAP1B
Regulation of Microtubule CytoskeletonTPPP;CFL2;MARK1;TESK2;MAP1B;DPYSL2;MARK2
Wnt Signaling Pathway NetPathMTAP1B;ANKRD6;HIPK2;NR5A1;PAX2;CRYBB2;ROR2;CSNK2A1P;SALL1

MAP1B has several biochemical functions, for example, microtubule binding, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP1B itself. We selected most functions MAP1B had, and list some proteins which have the same functions with MAP1B. You can find most of the proteins on our site.

Function Related Protein
microtubule bindingHAUS8;RAB11A;KIF27;KIF5A;FAM154A;KIFC3;KIF5AA;KCNH2A;KIF23
protein bindingANKS4B;TRIM42;BMI1;LYN;TRAF6;RNF146;PTPN18;MTERFD2;EPB49
structural molecule activityCLDN23;MAP4;CLDNH;COL18A1;SPRR2G;CKI;LAMA3;SEPT4;KRT23

MAP1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP1B here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP1B.

STK4; MAP1LC3B; TP53; RASSF5; GAN

Research Area

Related articles

El Fatimy, R; Tremblay, S; et al. Fragile Mental Retardation Protein Interacts with the RNA-Binding Protein Caprin1 in Neuronal RiboNucleoProtein Complexes. PLOS ONE 7:-(2012).
Rudrabhatla, P; Jaffe, H; et al. Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs. FASEB JOURNAL 25:3896-3905(2011).
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