• Official Full Name

    microtubule-associated protein 2

  • Background

    This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
  • Synonyms

    MAP2; microtubule-associated protein 2; MAP2A; MAP2B; MAP2C; MAP-2;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • C
    • Myc
    • DDK
    • His
    • His (Fc)
    • Avi
    • His|GST
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAP2-28460TH Recombinant Human MAP2 Wheat Germ N/A
    Human MAP2-047H Recombinant Human MAP2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human MAP2-4512HCL Recombinant Human MAP2 293 Cell Lysate HEK293 N/A
    Human MAP2-284H Recombinant Human MAP2 Mammalian Cell His
    Human MAP2-6820H Recombinant Human MAP2 protein, His-tagged E.coli His
    Human MAP2-3919H Recombinant Human MAP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MAP2-1351H-B Recombinant Human MAP2 Protein Pre-coupled Magnetic Beads HEK293
    Human MAP2-1351H Recombinant Human MAP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Map2-3919M Recombinant Mouse Map2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Map2-3201M Recombinant Mouse Map2 protein, His-SUMO-tagged E.coli His-SUMO
    Mouse Map2-5462M Recombinant Mouse Map2 protein, His-tagged Yeast His
    Mouse Map2-6821M Recombinant Mouse Map2 protein, His & GST-tagged E.coli His/GST
    Rat Map2-6822R Recombinant Rat Map2 protein, His & GST-tagged E.coli His/GST
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Map2 Related Articles
    • Map2 Related Research Area

    Map2 involved in several pathways and played different roles in them. We selected most pathways Map2 participated on our site, such as LKB1 signaling events, MAPK Cascade, SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Map2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    LKB1 signaling eventsMAP2;CDC37;CTSD;MARK4;SIK3;MARK2;STK11IP
    SIDS Susceptibility PathwaysMBD1;PLP1;CC2D1A;DLX2;FOXM1;CHRFAM7A;TPH2;SNTA1;MAZ

    Map2 has several biochemical functions, for example, calmodulin binding, dystroglycan binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Map2 itself. We selected most functions Map2 had, and list some proteins which have the same functions with Map2. You can find most of the proteins on our site.

    Function Related Protein
    calmodulin bindingEDF1;ATP2B4;TRPM4;TRPV4;KCNN1A;MIP;PPP3CC;MAPKAPK5;PHKA2
    dystroglycan bindingMAP2;AGR2;DAG1;VCL;DMD;GYLTL1B;AGR3;CLASP1;AGRN
    protein bindingIL10RB;OTUD7B;RBL1;CTLA2B;CEBPG;FAS;NAP1L1;IL36RN;BBS7
    structural molecule activityTUBA1B;CLDN5A;FGA;LOR;CLDN22;KRT40;CLDN9;ISCA1;TUBB

    Map2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Map2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Map2.

    GRB2; CalpB; JUNB; MDM2; CBFB; SCHIP1; 3',5'-cyclic amp; 8-aha-camp; 8-aha-omethyladenosine; PTBP3; p27958-pro_0000037566

    Cherry, JF; Bennett, NK; et al. Engineered N-cadherin and L1 biomimetic substrates concertedly promote neuronal differentiation, neurite extension and neuroprotection of human neural stem cells. ACTA BIOMATERIALIA 10:4113-4126(2014).
    Liang, CM; Weng, SJ; et al. Neurotrophic and neuroprotective potential of human limbus-derived mesenchymal stromal cells. CYTOTHERAPY 16:1371-1383(2014).
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