Recombinant Human MAP2

• Cat.No.: MAP2-28460TH
• Product Overview: Recombinant full length Human MAP2 with N terminal proprietary tag; Predicted MWt 77.88 kDa.

Specification

• Description: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
• Protein length: 471 amino acids
• Molecular Weight: 77.880kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEG LVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELT SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALA PSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTP GSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAI LVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRH RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVK IDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN VSSSGSINLLESPQLATLAEDVTAALAKQGL
• Sequence Similarities: Contains 3 Tau/MAP repeats.

Gene Information

• Gene Name: MAP2 microtubule-associated protein 2 [ Homo sapiens ]
• Official Symbol: MAP2
• Synonyms: MAP2; microtubule-associated protein 2; MAP2A; MAP2B; MAP2C
• Gene ID: 4133
• mRNA Refseq: NM_001039538
• Protein Refseq: NP_001034627
• MIM: 157130
• Uniprot ID: P11137
• Chromosome Location: 2q34-q35
• Pathway: LKB1 signaling events, organism-specific biosystem; MAPK Cascade, organism-specific biosystem
• Function: beta-dystroglycan binding; calmodulin binding; protein binding; structural molecule activity