MAPK4

Erk3, also known as MAPK6 or p97 MAPK, is almost 50% identical to Erk1/2 at the kinase domain located in its amino-terminal region. However, Erk3 is distinguished from other MAP kinases in that it lacks the conserved TXY motif in its activation loop, poss Encodes a nuclear and cytoplasmically localized MAP kinase involved in mediating responses to pathogens. Its substrates include MKS1 and probably MAP65-1.The MAP65-1 interaction is involved in mediating cortical microtuble organization.

MAPK4; mitogen-activated protein kinase 4; PRKM4; Erk3 related; Erk4; ERK-4; MAPK 4; p63-MAPK; Erk3-related; MAP kinase 4; MAP kinase isoform p63; extracellular signal-regulated kinase 4; ERK3; p63MAPK; MPK4; ATMPK4; MAP kinase 4 (MPK4); FUNCTIONS IN: MAP kinase activity, kinase activity; INVOLVED IN: in 14 processes; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), JNK MAP kinase (InterPro:IPR008351), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), MAP kinase, conserved site (InterPro:IPR003527), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: MAP kinase 11 (TAIR:AT1G01560.2); Has 123445 Blast hits to 122024 proteins in 4656 species: Archae - 100; Bacteria - 13145; Metazoa - 47072; Fungi - 12439; Plants - 29862; Viruses - 477; Other Eukaryotes - 20350 (source: NCBI BLink).; F2N1.1; F2N1_1;