Recombinant Human MAPK4 Protein (A2-W587), His/GST tagged

• Cat.No.: MAPK4-0111H
• Product Overview: Recombinant Human 8His-GST-TEV-GG-MAPK4(A2-W587 end) Protein was expressed in Insect cell.

Specification

• Description: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.
• Source: Insect cell
• Species: Human
• Tag: His/GST
• Form: Liquid
• Protein Length: A2-W587
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: MAPK4 mitogen-activated protein kinase 4 [ Homo sapiens (human) ]
• Official Symbol: MAPK4
• Synonyms: MAPK4; mitogen-activated protein kinase 4; PRKM4; Erk3 related; Erk4; ERK-4; MAPK 4; p63-MAPK; Erk3-related; MAP kinase 4; MAP kinase isoform p63; extracellular signal-regulated kinase 4; ERK3; p63MAPK
• Gene ID: 5596
• mRNA Refseq: NM_002747
• Protein Refseq: NP_002738
• MIM: 176949
• UniProt ID: P31152