MAPK8IP3 Protein

MAPK8IP3

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MAPK8IP3

Official Full Name mitogen-activated protein kinase 8 interacting protein 3
Background The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Synonyms MAPK8IP3; mitogen-activated protein kinase 8 interacting protein 3; C-Jun-amino-terminal kinase-interacting protein 3; homolog of Drosophila Sunday driver 2; JIP3; JSAP1; KIAA1066; syd; FLJ00027; JNK / Stress Activated Protein Kinase Associated Protein 1; JNK Interacting Protein 3; Mitogen Activated Protein kinase 8 Interacting Protein 3; JIP-3; JNK-interacting protein 3; JNK/SAPK-associated protein-1; JNK MAP kinase scaffold protein 3; C-jun-amino-terminal kinase interacting protein 3; JNK/stress-activated protein kinase-associated protein 1; mitogen-activated protein kinase 8-interacting protein 3; SYD2
    • Species :
    • Mouse
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse MAPK8IP3-9541M Recombinant Mouse MAPK8IP3 Protein Mammalian Cell His Inquiry
    Zebrafish MAPK8IP3-8491Z Recombinant Zebrafish MAPK8IP3 Mammalian Cell His Inquiry

    MAPK8IP3 involved in several pathways and played different roles in them. We selected most pathways MAPK8IP3 participated on our site, such as MAPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK8IP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway RAC3B; TRAF2; CACNA2D1A; MAP3K4; RASGRP3; MAP2K4B; MAPK4; FGF19; MAP3K12; RPS6KA5

    MAPK8IP3 has several biochemical functions, for example, JUN kinase binding, MAP-kinase scaffold activity, kinesin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK8IP3 itself. We selected most functions MAPK8IP3 had, and list some proteins which have the same functions with MAPK8IP3. You can find most of the proteins on our site.

    Function Related Protein
    JUN kinase binding SPAG9A; GSTP1; MAPK8IP3; PTK2; MAD2L2; SPAG9
    MAP-kinase scaffold activity CD36; DUSP19; KSR1; MAPK8IP2; MAPK8IP3; JIP1; SPAG9; SPAG9A
    kinesin binding NUP62; DISC1; TOR1A; ACTB; KIFAP3B; ATCAY; JIP1; KIF1B; ARPC2; PIFO
    mitogen-activated protein kinase kinase binding TRIB1; IGBP1; PIN1; TAOK2; MAPK8IP3; RAF1; ARRB1; DLG1; ACE; TRIB3
    mitogen-activated protein kinase kinase kinase binding MAP3K11; MAPK8IP3; MAPK9; STK38; TRAF6; PPEF2; MARVELD3; TCF3; CDC42; MAP4K2
    protein binding ZG16; DAB1; GTPBP10; STAP1; BAZ2B; MYH7B; KCNE4; TFAP2A; CDKN1B; PEX19
    receptor signaling complex scaffold activity RGS14; SPAG9; GRIP2A; NCK2; MAPK8IP3; AXIN1; CD3G; SHANK1; NCK1; CARD10

    MAPK8IP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK8IP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK8IP3.

    Klc1; Klc2; Arf6

    Gunawardhana, LP; Baines, KJ; et al. Differential DNA Methylation Profiles of Infants Exposed to Maternal Asthma During Pregnancy. PEDIATRIC PULMONOLOGY 49:852-862(2014).
    Cho, IH; Lee, KW; et al. JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains. EXPERIMENTAL AND MOLECULAR MEDICINE 43:462-470(2011).

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