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Official Full Name microtubule associated serine/threonine kinase-like
Background This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.
Synonyms MASTL; microtubule associated serine/threonine kinase-like; serine/threonine-protein kinase greatwall; FLJ14813; THC2; 2700091H24Rik; C88295; GW; GWL; GWL_HUMAN; hGWL; MAST-L; MGC117975; microtubule associated serine/threonine kinase like; Microtubule-associated serine/threonine-protein kinase-like; RP11 85G18.2; greatwall protein kinase; GREATWALL; RP11-85G18.2
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Mastl-3968M Recombinant Mouse Mastl Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MASTL-156H Recombinant Human MASTL Protein, GST-tagged, Active Insect Cell GST
    Human MASTL-4456HCL Recombinant Human MASTL 293 Cell Lysate HEK293 N/A
    Human MASTL-757H Recombinant Human MASTL, His-tagged E.coli His
    Mouse MASTL-9582M Recombinant Mouse MASTL Protein Mammalian Cell His
    Zebrafish MASTL-1035Z Recombinant Zebrafish MASTL Mammalian Cell His

    mastl involved in several pathways and played different roles in them. We selected most pathways mastl participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with mastl were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle, Mitotic GMNN; MASTL; CDKN2A; BLZF1; MYCA; TUBG1; LMNB1; CEP63; E2F2; NCAPH
    MASTL Facilitates Mitotic Progression ARPP19B; ENSA; ARPP19; ARPP19A; ENSAB; MASTL; ENSAA
    Mitotic Prophase SET; VRK1; ENSAB; ARPP19; MASTL; SETB; NEK7; NCAPD3; NEK9; SMC2

    mastl has several biochemical functions, for example, ATP binding, kinase activity, protein phosphatase 2A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by mastl itself. We selected most functions mastl had, and list some proteins which have the same functions with mastl. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding GRK6; PIK3C2G; ABCB9; DDX51; GK2; HSPA1B; KIF4; MAP4K2; IGF1R; PIKFYVE
    kinase activity CDK14; GUK1B; PRKRIRA; PKMYT1; PI4KAP2; KITB; CAMK2D1; ALPK2; MASTL; PTK2AB
    protein phosphatase 2A binding SPHK1; ANKLE2; PTPN1; STRN; PPME1; STRN4; ENSA; BCL2; CTTNBP2NL; ARPP19
    protein serine/threonine kinase activity CLK1; PIM3; RIPK2; ULK2; RIPK4; SIK2; PLK3; ADCK2; ICK; BMPR1AA

    mastl has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mastl here. Most of them are supplied by our site. Hope this information will be useful for your research of mastl.

    Dynll1; MED26; SSFA2; TAP2; CDK18; RPS6KA1; SLC1A5; MRPL2; ACBD5; CEP85; FASTKD5; TMEM263; PLEKHA8; DERL2; EPB41L5; UBN1; TELO2

    Wang, L; Fisher, LA; et al. Monoclonal Antibodies Against Xenopus Greatwall Kinase. HYBRIDOMA 30:469-474(2011).

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