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Official Full Name mediator complex subunit 30
Background The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010]
Synonyms MED30; mediator complex subunit 30; MED30S; THRAP6; TRAP25; mediator of RNA polymerase II transcription subunit 30; TRAP/Mediator complex component TRAP25; thyroid hormone receptor associated protein 6; thyroid hormone receptor-associated protein 6; putative mediator of RNA polymerase II transcription subunit 30; thyroid hormone receptor-associated protein complex 25 kDa component;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MED30-4383HCL Recombinant Human MED30 293 Cell Lysate HEK293 N/A
    Human MED30-66H Recombinant Human MED30 protein, His-tagged E.coli His
    Human MED30-813H Recombinant Human MED30, His-tagged E.coli His
    Mouse Med30-4019M Recombinant Mouse Med30 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse MED30-9702M Recombinant Mouse MED30 Protein Mammalian Cell His
    Rhesus Macaque MED30-2725R Recombinant Rhesus monkey MED30 Protein, His-tagged Mammalian Cell His
    Chicken MED30-4837C Recombinant Chicken MED30 Mammalian Cell His
    Chicken MED30-4839C Recombinant Chicken MED30 Mammalian Cell His
    Zebrafish MED30-10981Z Recombinant Zebrafish MED30 Mammalian Cell His

    med30 involved in several pathways and played different roles in them. We selected most pathways med30 participated on our site, such as Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with med30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Thyroid hormone signaling pathway EP300; PLN; RHEB; ATP1B1; HDAC3; PLCD4; CCND1; CASP9; ATP1B4; MED14

    med30 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by med30 itself. We selected most functions med30 had, and list some proteins which have the same functions with med30. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II transcription cofactor activity NKX2; THRAP3; TDG; MED12; MED30; PPRC1; MED11; MED18; MED17; MED13A
    ligand-dependent nuclear receptor transcription coactivator activity ATXN7L3; CCAR1; SLC30A9; PPRC1; SMARCD3; THRAP3; WDR77; PUS1; MED14; ACTN4
    protein binding TCEA1; GPR37; FAM86C; PHF21A; NKX2; TMUB2; RNH1; CASR; UBXN2B; RFC2
    receptor activity CHRM3; RET; GRIN2BB; CD200R2; NLGN4B; OGFRL2; PVRL4; CCR6; SLC1A5; TIGIT
    thyroid hormone receptor binding NCOR1; MED16; FUS; PRMT2; MED4; MED12; NUP62; NSD1; NCOA3; GTF2B
    transcription cofactor activity THRAP3; MED4; MAX; MED13; PTPN14; MED14; PIR; ZNF671; KAT2B; ZNF763
    vitamin D receptor binding MED17; MED30; RXRA; TAF7; MED4; SNW1; MED14; MED1; MED16; TAF11

    med30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with med30 here. Most of them are supplied by our site. Hope this information will be useful for your research of med30.

    MED10; KRTAP10-9; DOCK8; CDK19; MED19; CDK8; MED9; MED26; PTBP3

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