Mll1

  • Official Full Name

    myeloid/lymphoid or mixed-lineage leukemia 1

  • Overview

    Histone-lysine N-methyltransferase HRX is an enzyme that in humans is encoded by the MLL (ALL1) gene. MLL stands for Myeloid/Lymphoid, or Mixed-Lineage, Leukemia.

  • Synonyms

    Mll1;myeloid/lymphoid or mixed-lineage leukemia 1;HRX;Mll;All1;ALL-1;Cxxc7;HTRX1;KMT2A;mKIAA4050;6430520K01
Cat.# Product name Source (Host) Species Tag Protein Length Price
MLL1-9881M Recombinant Mouse MLL1 Protein Mammalian Cells Mouse His
Kit-1781 MLL1 Complex Chemiluminescent Assay Kit Non
Kit-1977 MLL1 SAM-Screener Assay Kit Non
MLL1-5582M Recombinant Mouse MLL1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MLL1-5582M-B Recombinant Mouse MLL1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Mll1 involved in several pathways and played different roles in them. We selected most pathways Mll1 participated on our site, such as Lysine degradation,Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with Mll1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Lysine degradation SETD7,MLL5,ALDH9A1A.1,ALDH7A1,PLOD2,HADHA,PLOD1A,WHSC1L1,GLT25D1,GCDH
    Transcriptional misregulation in cancer SIX4,RARA,PAX7,SIN3A,IL1R2,HIST1H3C,CD14,H3F3C,SP1,PAX5

    Protein Function

    Mll1 has several biochemical functions, for example, DNA binding,chromatin binding,core promoter sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Mll1 itself. We selected most functions Mll1 had, and list some proteins which have the same functions with Mll1. You can find most of the proteins on our site.

    Function Related Protein
    transcription regulatory region DNA binding ARRB1,ZNF335,CEBPA,NKX2,NKX3-1,TCF7,SFPQ,Ar,KLF15,KLF1
    protein binding JAG1,NITR9,TCF7L2,HSPA12B,ISYNA1,SPC24,INHBB,MAD2L1BP,PLSCR3,EPB41
    chromatin binding ENY2,RELA,C10orf119,JARID2,MB21D2,EOMES,EBF2,DHX30,SMAD4,SP140L
    zinc ion binding MMP14B,TCEA1,PHF21A,BTR29,S100A5,DTX1,GM757,RNF11A,RAG1,TRIM35
    core promoter sequence-specific DNA binding C1orf51,PRMT5,CREM,ESR2,TP53,SOHLH2,PPARG,ESR1,SIRT1,SP1
    DNA binding DTD1,ZNF358,SYCP2,UHRF2,RBM6,ZFP36,POLR1C,MSL3,HEMK1,PA2G4
    histone methyltransferase activity (H3-K4 specific) MLL5,SETD3,KMT2E,SETMAR,WHSC1L1,WDR82,ASH1L,KMT2A,SMYD1B,WBP7
    identical protein binding SH3GL3,HOMER1,DCP1A,MRAP2,CHEK2,SMN2,LDHA,RCAN1,VIM,KIRRELA
    metal ion binding ACACA,ITGB1BP3,NGLY1,A3GALT2,MYO9B,CA15C,CYP8B3,LFNG,ZFY2,CYP2P7

    Interacting Protein

    Mll1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Mll1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Mll1.

    siglecg_mouse_gene;Rbbp5

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