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Recombinant Rat MMP7 Protein (98-267 aa), GST-tagged

Cat.No. : MMP7-659R
Product Overview : Recombinant Rat MMP7 Protein (98-267 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Protein Description: Full Length of Mature Protein.
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  • Gene Information
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Description : Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
Source : E. coli
Species : Rat
Tag : GST
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 45.9 kDa
Protein length : 98-267 aa
AA Sequence : FSLMPNSPKWHSRTVTYRIVSYTTD LPRFLVDQIVKRALRMWSMQIPLNF KRVSWGTADIIIGFARGDHGDNFPF DGPGNTLGHAFAPGPGLGGDAHFDK DEYWTDGEDSGVNFLFVATHELGHS LGLGHSSVPSSVMYPTYQGDHSEDF SLTKDDIAGIQKLYGKRNKL
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Gene Name : Mmp7 matrix metallopeptidase 7 [ Rattus norvegicus ]
Official Symbol : MMP7
Synonyms : MMP7; matrilysin; MMP-7; matrin; pump-1 protease; MPMM;
Gene ID : 25335
mRNA Refseq : NM_012864
Protein Refseq : NP_036996
UniProt ID : P50280

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What clinical conditions are associated with MMP7 overexpression? 01/31/2023

MMP7 overexpression has been linked to various diseases, including cancer, inflammatory disorders, and tissue fibrosis.

In what ways does MMP7 contribute to inflammatory processes? 05/20/2020

MMP7 is involved in the degradation of extracellular matrix components during inflammation, influencing tissue damage and repair processes.

How can MMP7 be targeted for therapeutic interventions? 01/20/2020

Developing specific inhibitors that target MMP7 activity is a potential approach for therapeutic interventions, particularly in diseases where MMP7 plays a detrimental role.

Are there any inhibitors developed for MMP7? 10/19/2017

Several MMP inhibitors have been investigated, and some show promise in controlling MMP7 activity. However, their clinical use is still under research.

How is MMP7 involved in cancer progression? 01/13/2017

MMP7 facilitates cancer cell invasion and metastasis by degrading the extracellular matrix, allowing cancer cells to invade surrounding tissues and spread to distant organs.

Can MMP7 be used as a biomarker for cancer diagnosis? 01/09/2016

Yes, elevated levels of MMP7 have been observed in the serum or tissues of cancer patients, making it a potential biomarker for certain types of cancer.

Customer Reviews (3)

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Reviews
05/01/2023

    This includes rigorous quality control measures to ensure the consistency and purity of the protein, thereby reducing variability in the experimental outcomes.

    05/13/2022

      by utilizing MMP7 protein in trials and collaborating with a supportive manufacturer, researchers can gain access to a versatile tool that can aid in their understanding of angiogenesis and vascular biology.

      05/26/2018

        With expert assistance and reliable product quality, researchers can conduct their experiments with confidence, enabling them to contribute to advancements in the field and potentially improve future therapeutic interventions.

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