MRPL1
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Official Full Name
mitochondrial ribosomal protein L1 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. -
Synonyms
MRPL1;mitochondrial ribosomal protein L1;39S ribosomal protein L1, mitochondrial;BM022;mitochondrial;39S ribosomal protein L1;39S ribosomal protein L1, mitochondrial precursor;L1mt;MRP L1;MRP-L1;RM01_HUMAN;OTTHUMP00000160703;OTTHUMP00000219156
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- His
- T7
- Non
- SUMO
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MRPL1-976H | Recombinant Human MRPL1, His-tagged | E.coli | Human | His | 1-303aa | |
| MRPL1-537H | Recombinant Human mitochondrial ribosomal protein L1, His-tagged | E.coli | Human | His | 51-325 a.a. |
|
| Mrpl1-7957M | Recombinant Mouse Mrpl1 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Glu143~Ala336 |
|
| Mrpl1-7958R | Recombinant Rat Mrpl1 protein, His & T7-tagged | E.coli | Rat | His&T7 | Pro141~Ala323 |
|
| MRPL1-8005Z | Recombinant Zebrafish MRPL1 | Mammalian Cells | Zebrafish | His |
|
|
| MRPL1-1132HCL | Recombinant Human MRPL1 cell lysate | Human | Non |
|
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| MRPL1-4850H | Recombinant Human MRPL1 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 51-324aa |
|
| MRPL1-5103H | Recombinant Human MRPL1 Protein (Pro147-Asn285), N-His tagged | E.coli | Human | His | Pro147-Asn285 |
|
| MRPL1-5553H | Recombinant Human MRPL1 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| MRPL1-6376HF | Recombinant Full Length Human MRPL1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 303 amino acids |
|
Involved Pathway
MRPL1 involved in several pathways and played different roles in them. We selected most pathways MRPL1 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPS16,MRPS2,MRPS12,RPS24,RPL5B,RSL24D1,RPS27L,RPS28,RPL22,RPLP0 |
Protein Function
MRPL1 has several biochemical functions, for example, poly(A) RNA binding,protein binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL1 itself. We selected most functions MRPL1 had, and list some proteins which have the same functions with MRPL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZNF350,SNIP1,MON2,ERBB2,FUBP3,NCSTN,NXT1,NOG,TMIGD2,USP2 |
| poly(A) RNA binding | ACAA2,MRPS14,SARS2,ANKHD1,MRPL42,PCBP2,LTA4H,CSDE1,NDUFV3,RCC2 |
| structural constituent of ribosome | MRPL42,SLC25A24L,MRPL36,RPL9,MRPL15,MRPS21,MRPL41,MRPL47,RPL14,MRPL51 |
Interacting Protein
MRPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL1.
GOPC;Brwd3;MRPL43;b4dln1_human;APBB2;MRPL42;ICT1;MRPL33;PRPF40A;PTTG1;SSB;MRPL3;PI4KA;BRCC3;MRPL19;MRPL12;YBX1;MRPL49
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References
- Arsenijevic, T; Gregoire, F; et al. Murine 3T3-L1 Adipocyte Cell Differentiation Model: Validated Reference Genes for qPCR Gene Expression Analysis. PLOS ONE 7:-(2012).
- Ren, JF; Shen, X; et al. The complete mitochondrial genome of the clam Meretrix petechialis (Mollusca: Bivalvia: Veneridae). MITOCHONDRIAL DNA 20:78-87(2009).
