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MRPL1

Official Full Name

mitochondrial ribosomal protein L1
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.
Synonyms

MRPL1; mitochondrial ribosomal protein L1; 39S ribosomal protein L1, mitochondrial; BM022; mitochondrial; 39S ribosomal protein L1; 39S ribosomal protein L1, mitochondrial precursor; L1mt; MRP L1; MRP-L1; RM01_HUMAN; OTTHUMP00000160703; OTTHUMP00000219156;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
SUMO
T7
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPL1-537H	Recombinant Human mitochondrial ribosomal protein L1, His-tagged	E.coli	His		Inquiry
Human	MRPL1-976H	Recombinant Human MRPL1, His-tagged	E.coli	His	1-303aa	$319 / 25μg
Human	MRPL1-1132HCL	Recombinant Human MRPL1 cell lysate		Non		Inquiry
Human	MRPL1-5553H	Recombinant Human MRPL1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MRPL1-5103H	Recombinant Human MRPL1 Protein (Pro147-Asn285), N-His tagged	E.coli	His	Pro147-Asn285	Inquiry
Human	MRPL1-4850H	Recombinant Human MRPL1 protein, His-SUMO-tagged	E.coli	His&SUMO	51-324aa	Inquiry
Human	MRPL1-6376HF	Recombinant Full Length Human MRPL1 Protein, GST-tagged	In Vitro Cell Free System	GST	303 amino acids	Inquiry
Mouse	Mrpl1-7957M	Recombinant Mouse Mrpl1 protein, His & T7-tagged	E.coli	His&T7	Glu143~Ala336 (Accession # Q99N96)	Inquiry
Rat	Mrpl1-7958R	Recombinant Rat Mrpl1 protein, His & T7-tagged	E.coli	His&T7	Pro141~Ala323 (Accession # B5DER4)	Inquiry
Zebrafish	MRPL1-8005Z	Recombinant Zebrafish MRPL1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

MRPL1 involved in several pathways and played different roles in them. We selected most pathways MRPL1 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome	RPS18;RPS15A;RPL26;RPS20;RPS28;MRPL4;RPS3A;RPS29;RPS27

MRPL1 has several biochemical functions, for example, poly(A) RNA binding, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL1 itself. We selected most functions MRPL1 had, and list some proteins which have the same functions with MRPL1. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	MSI2;FXR1;DDX10;RTF1;RPL23A;MRPL3;RBM10;HMGB3;RBM47
protein binding	RTN4RL2A;NME1;CRIPT;KXD1;SSBP3;FAM133A;LINGO1;NUP37;SKA1
structural constituent of ribosome	MRPL51;UBA52;MRPS16;MRPS22;RPS12;MRPS5;RPS27.1;DAP3;MRPS6

MRPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL1.

GOPC; Brwd3; MRPL43; b4dln1_human; APBB2; MRPL42; ICT1; MRPL33; PRPF40A; PTTG1; SSB; MRPL3; PI4KA; BRCC3; MRPL19; MRPL12; YBX1; MRPL49

Research Area

Arsenijevic, T; Gregoire, F; et al. Murine 3T3-L1 Adipocyte Cell Differentiation Model: Validated Reference Genes for qPCR Gene Expression Analysis. PLOS ONE 7:-(2012).

Ren, JF; Shen, X; et al. The complete mitochondrial genome of the clam Meretrix petechialis (Mollusca: Bivalvia: Veneridae). MITOCHONDRIAL DNA 20:78-87(2009).