MRPL1

  • Official Full Name

    mitochondrial ribosomal protein L1

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.
  • Synonyms

    MRPL1; mitochondrial ribosomal protein L1; 39S ribosomal protein L1, mitochondrial; BM022; mitochondrial; 39S ribosomal protein L1; 39S ribosomal protein L1, mitochondrial precursor; L1mt; MRP L1; MRP-L1; RM01_HUMAN; OTTHUMP00000160703; OTTHUMP00000219156;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His|T7
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL1-537H Recombinant Human mitochondrial ribosomal protein L1, His-tagged E.coli His
Human MRPL1-976H Recombinant Human MRPL1, His-tagged E.coli His 1-303aa
Human MRPL1-1132HCL Recombinant Human MRPL1 cell lysate N/A
Human MRPL1-5553H Recombinant Human MRPL1 Protein, GST-tagged Wheat Germ GST
Human MRPL1-5103H Recombinant Human MRPL1 Protein (Pro147-Asn285), N-His tagged E.coli N-His Pro147-Asn285
Human MRPL1-4850H Recombinant Human MRPL1 protein, His-SUMO-tagged E.coli His-SUMO 51-324aa
Human MRPL1-6376HF Recombinant Full Length Human MRPL1 Protein, GST-tagged In Vitro Cell Free System GST 303 amino acids
Mouse Mrpl1-7957M Recombinant Mouse Mrpl1 protein, His & T7-tagged E.coli His/T7 Glu143~Ala336 (Accession # Q99N96)
Rat Mrpl1-7958R Recombinant Rat Mrpl1 protein, His & T7-tagged E.coli His/T7 Pro141~Ala323 (Accession # B5DER4)
Zebrafish MRPL1-8005Z Recombinant Zebrafish MRPL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MRPL1 involved in several pathways and played different roles in them. We selected most pathways MRPL1 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RibosomeRPL15;MRPS12;RPL10;RPL17;RPS12;RPS10-NUDT3;MRPL17;RPS17;RPS8B

MRPL1 has several biochemical functions, for example, poly(A) RNA binding, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL1 itself. We selected most functions MRPL1 had, and list some proteins which have the same functions with MRPL1. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingCCT4;ZCCHC24;EIF2C3;ZFP106;KIAA1429;PRRC2A;PKM2;HELZ2;TSNAX
protein bindingATE1;CTNNA2;THY1;F10;TBPL1;SUPT6H;NPL;TNK2;PTRF
structural constituent of ribosomeRPL26L1;MRPL4;RPL35;MRPL1;RPS16;RPS15A;MRPS9;MRPS12;MRPL42

MRPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL1.

GOPC; Brwd3; MRPL43; b4dln1_human; APBB2; MRPL42; ICT1; MRPL33; PRPF40A; PTTG1; SSB; MRPL3; PI4KA; BRCC3; MRPL19; MRPL12; YBX1; MRPL49

Research Area

Related articles

Arsenijevic, T; Gregoire, F; et al. Murine 3T3-L1 Adipocyte Cell Differentiation Model: Validated Reference Genes for qPCR Gene Expression Analysis. PLOS ONE 7:-(2012).
Ren, JF; Shen, X; et al. The complete mitochondrial genome of the clam Meretrix petechialis (Mollusca: Bivalvia: Veneridae). MITOCHONDRIAL DNA 20:78-87(2009).
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