MRPL15
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Official Full Name
mitochondrial ribosomal protein L15 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. -
Synonyms
MRPL15;mitochondrial ribosomal protein L15;39S ribosomal protein L15, mitochondrial;HSPC145;L15mt;MRP L7;MRP L15;RPML7;39S ribosomal protein L15;39S ribosomal protein L15 mitochondrial;MRPL 15;RPML 7;OTTHUMP00000226445;OTTHUMP00000226575;MRP-L7;MRP-L15
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- GST
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MRPL15-982H | Recombinant Human MRPL15, His-tagged | E.coli | Human | His | 1-296aa | |
| MRPL15-10047M | Recombinant Mouse MRPL15 Protein | Mammalian Cells | Mouse | His |
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| MRPL15-1530C | Recombinant Chicken MRPL15 | Mammalian Cells | Chicken | His |
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| MRPL15-885Z | Recombinant Zebrafish MRPL15 | Mammalian Cells | Zebrafish | His |
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| MRPL15-4194HCL | Recombinant Human MRPL15 293 Cell Lysate | HEK293 | Human | Non |
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| MRPL15-5559H | Recombinant Human MRPL15 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MRPL15-5688M | Recombinant Mouse MRPL15 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| MRPL15-5688M-B | Recombinant Mouse MRPL15 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MRPL15-6385HF | Recombinant Full Length Human MRPL15 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 296 amino acids |
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Involved Pathway
MRPL15 involved in several pathways and played different roles in them. We selected most pathways MRPL15 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | MRPS18A,RPL37A,MRPL17,RPL23A,RPS13,RPL17,RPL10,RPL12,RPL36AL,MRPL13 |
Protein Function
MRPL15 has several biochemical functions, for example, poly(A) RNA binding,protein binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL15 itself. We selected most functions MRPL15 had, and list some proteins which have the same functions with MRPL15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | SLC25A47A,RPL26L1,RPL7,RPSA,MRPL33,RPL10L,RPLP2,RPL36A,RPS9,RPL23 |
| protein binding | KSR1,PLCG1,BACE1,CRHR1,CD5,AMY1B,MPRIP,DDRGK1,TRPC7,SLC4A1 |
| poly(A) RNA binding | TIAL1,FMR1,DDX31,PEG10,H1FX,EIF4G2,HLTF,U2AF2,RPL13A,NOP2 |
Interacting Protein
MRPL15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL15 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL15.
CCNDBP1;RUNDC3A;ssrna_ug;Zfp36;YBX1;ICT1;NOP9;SLX4;MRPL50;MRPL9;MRPL1
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References
- Koc, EC; Burkhart, W; et al. The large subunit of the mammalian mitochondrial ribosome - Analysis of the complement of ribosomal proteins present. JOURNAL OF BIOLOGICAL CHEMISTRY 276:43958-43969(2001).
