MRPL15

  • Official Full Name

    mitochondrial ribosomal protein L15

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.
  • Synonyms

    MRPL15; mitochondrial ribosomal protein L15; 39S ribosomal protein L15, mitochondrial; HSPC145; L15mt; MRP L7; MRP L15; RPML7; 39S ribosomal protein L15; 39S ribosomal protein L15 mitochondrial; MRPL 15; RPML 7; OTTHUMP00000226445; OTTHUMP00000226575; MRP-L7; MRP-L15;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL15-982H Recombinant Human MRPL15, His-tagged E.coli His 1-296aa
Human MRPL15-4194HCL Recombinant Human MRPL15 293 Cell Lysate HEK293 N/A
Human MRPL15-5559H Recombinant Human MRPL15 Protein, GST-tagged Wheat Germ GST
Human MRPL15-6385HF Recombinant Full Length Human MRPL15 Protein, GST-tagged In Vitro Cell Free System GST 296 amino acids
Mouse MRPL15-10047M Recombinant Mouse MRPL15 Protein Mammalian Cell His
Mouse MRPL15-5688M Recombinant Mouse MRPL15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MRPL15-5688M-B Recombinant Mouse MRPL15 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MRPL15-885Z Recombinant Zebrafish MRPL15 Mammalian Cell His
Chicken MRPL15-1530C Recombinant Chicken MRPL15 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MRPL15 involved in several pathways and played different roles in them. We selected most pathways MRPL15 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RibosomeRPL31;RPL6;MRPL23;RPS19;MRPS17;FAUA;RPS8A;RPL34-PS1;MRPS5

MRPL15 has several biochemical functions, for example, poly(A) RNA binding, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL15 itself. We selected most functions MRPL15 had, and list some proteins which have the same functions with MRPL15. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingApi5;MYO5A;HELZ;RBM12;PURG;SAFB;CLNS1A;MRPL42;GPATCH8
protein bindingNRIP3;MCL1;EIF4G1;DIAPH1;SF3B3;ZNF238;RABGAP1L;ZBTB25;ACVR1
structural constituent of ribosomeRPS4Y1;RPS27.1;RPS11;RPL10A;RPS8;MRPS22;RPL24;RPL29;RPL6

MRPL15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL15 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL15.

CCNDBP1; RUNDC3A; ssrna_ug; Zfp36; YBX1; ICT1; NOP9; SLX4; MRPL50; MRPL9; MRPL1

Research Area

Related articles

Koc, EC; Burkhart, W; et al. The large subunit of the mammalian mitochondrial ribosome - Analysis of the complement of ribosomal proteins present. JOURNAL OF BIOLOGICAL CHEMISTRY 276:43958-43969(2001).
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