MRPL39

  • Official Full Name

    mitochondrial ribosomal protein L39

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

  • Synonyms

    MRPL39;mitochondrial ribosomal protein L39;RPML5;MRP-L5;PRED22;PRED66;FLJ20451

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Human
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • DDK
  • Myc
  • GST
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
MRPL39-10066M Recombinant Mouse MRPL39 Protein Mammalian Cells Mouse His
MRPL39-10284Z Recombinant Zebrafish MRPL39 Mammalian Cells Zebrafish His
MRPL39-4173HCL Recombinant Human MRPL39 293 Cell Lysate HEK293 Human Non
Mrpl39-4156M Recombinant Mouse Mrpl39 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
MRPL39-5582H Recombinant Human MRPL39 Protein, GST-tagged Wheat Germ Human GST
MRPL39-5701M Recombinant Mouse MRPL39 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MRPL39-5701M-B Recombinant Mouse MRPL39 Protein Pre-coupled Magnetic Beads HEK293 Mouse
MRPL39-5705H Recombinant Human MRPL39 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
MRPL39-6407HF Recombinant Full Length Human MRPL39 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 333 amino acids

    Involved Pathway

    MRPL39 involved in several pathways and played different roles in them. We selected most pathways MRPL39 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL39 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitochondrial translation elongation MRPL40,MRPS31,MRPS22,MRPL45,MRPL48,MRPL54,MRPS35,CHCHD1,MRPS34,MRPL53
    Organelle biogenesis and maintenance TCTEX1D2,CEP97,AURKAIP1,DYNLL2A,TRIP11,UNC119.1,TSFM,GFM2,WDR34,TFB1M
    Mitochondrial translation MRPS33,MRPL51,MRPS36,GFM2,MRPL10,MRPL3,MRPS35,MRPS22,MRPL45,MRPL28
    Mitochondrial translation termination MTRF1L,MRPS27,MRPL46,MRPL40,MRPL45,MRPL51,MRPS25,MRPS31,MRPS36,MRPL54
    Mitochondrial translation initiation MRPS26,MRPL48,MRPL50,MRPL49,MRPL47,DAP3,MTIF3,CHCHD1,MRPL52,MRPS23

    Protein Function

    MRPL39 has several biochemical functions, for example, nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL39 itself. We selected most functions MRPL39 had, and list some proteins which have the same functions with MRPL39. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding GTF2F1,FKBP3,ADAR,SNIP1,HNRNPH2,LARP2,PABPN1,SRPR,ACAA2,HIST1H4B
    nucleotide binding SFRS3A,ATP2B3B,CAMK2D2,ATP2A2A,RAB25A,ABCA13,CPEB2,CAMK2D1,TNRC6B,RHOT1A

    Interacting Protein

    MRPL39 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL39 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL39.

    PAN2;USP32;Gtf3c4;MRPL50;MRPL9;MRPL1;SIRT4;Mad2l1

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