|Official Full Name||mitochondrial ribosomal protein L43|
|Background||Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms.|
|Synonyms||MRPL43; mitochondrial ribosomal protein L43; 39S ribosomal protein L43, mitochondrial; bMRP36a; mitochondrial; 39S ribosomal protein L43; L43mt; Mitochondrial ribosomal protein bMRP36a; MRP L43; MRP-L43; RM43_HUMAN|
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mrpl43 involved in several pathways and played different roles in them. We selected most pathways mrpl43 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with mrpl43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
mrpl43 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by mrpl43 itself. We selected most functions mrpl43 had, and list some proteins which have the same functions with mrpl43. You can find most of the proteins on our site.
mrpl43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mrpl43 here. Most of them are supplied by our site. Hope this information will be useful for your research of mrpl43.
FXR2; VCAM1; SRPK1; EIF1B; ARRB2; Ybx1; DDX56; YBX1; ICT1