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  • Official Full Name

    mitochondrial ribosomal protein L49

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.
  • Synonyms

    MRPL49; mitochondrial ribosomal protein L49; C11orf4, chromosome 11 open reading frame 4; 39S ribosomal protein L49, mitochondrial; L49mt; neighbor of FAU; next to FAU; NOF; NOF1; 39S ribosomal protein L49 mitochondrial; C11orf4; Chromosome 11 open reading frame 4; MGC10656; MRP L49; Protein NOF1; RM49; MRP-L49;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL49-1012H Recombinant Human MRPL49, His-tagged E.coli His 1-166aa
Human MRPL49-4160HCL Recombinant Human MRPL49 293 Cell Lysate HEK293 N/A
Human MRPL49-6437HF Recombinant Full Length Human MRPL49 Protein, GST-tagged In Vitro Cell Free System GST 166 amino acids
Human MRPL49-5592H Recombinant Human MRPL49 Protein, GST-tagged Wheat Germ GST
Mouse MRPL49-10076M Recombinant Mouse MRPL49 Protein Mammalian Cell His
Mouse MRPL49-5707M Recombinant Mouse MRPL49 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MRPL49-5707M-B Recombinant Mouse MRPL49 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey MRPL49-706C Recombinant Cynomolgus MRPL49 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey MRPL49-452C-B Recombinant Cynomolgus Monkey MRPL49 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey MRPL49-452C Recombinant Cynomolgus Monkey MRPL49 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MRPL49-2848R Recombinant Rhesus monkey MRPL49 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MRPL49-2668R Recombinant Rhesus Macaque MRPL49 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MRPL49-2668R-B Recombinant Rhesus Macaque MRPL49 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MRPL49 involved in several pathways and played different roles in them. We selected most pathways MRPL49 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL49 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mitochondrial translationMRPL47;GADD45GIP1;MRPS30;MRPS36;MRPS34;MRPL52;MRPL55;TUFM;MRPS25
Mitochondrial translation elongationMRPS23;TSFM;MRPS28;MRPL50;MRPL47;MRPL53;MRPS30;MRPL52;MRPS24
Mitochondrial translation initiationMRPL37;MRPL3;MRPS27;MRPL47;MRPL39;MRPL28;MRPL46;MRPS22;MTFMT
Mitochondrial translation terminationAURKAIP1;MRPL46;MRPL53;DAP3;MRPS25;MRPS27;MTRF1L;MRPL44;MRPL47
Organelle biogenesis and maintenanceMRPL44;MRPS22;MARK4;PTCD3;TCTN1;MRPS24;IFT22;GADD45GIP1;IFT74

MRPL49 has several biochemical functions, for example, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL49 itself. We selected most functions MRPL49 had, and list some proteins which have the same functions with MRPL49. You can find most of the proteins on our site.

Function Related Protein
structural constituent of ribosomeFAUB;MRPS18C;RPS17;SLC25A47A;RPSA;MRPL16;MRPS16;MRPL21;DAP3

MRPL49 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL49 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL49.

Brwd3; YBX1; ICT1; Fbxw11; Osgep; Spire2; MRPL50; MRPL9; MRPL1; Ecd

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