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MUC20

Official Full Name

mucin 20, cell surface associated
Overview

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

MUC20; mucin 20, cell surface associated; mucin-20; FLJ14408; KIAA1359; MUC 20; MUC-20; MUC20_HUMAN; Mucin 20; Transmembrane mucin MUC20S;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse
Rat

Source

E.coli
In Vitro Cell Free System
Wheat Germ

Tag

GST
His|GST
N/A
N
His

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MUC20-1108H	Recombinant Human MUC20, GST-tagged	E.coli	GST	255-555aa	$319 / 25ug
Human	MUC20-1154HCL	Recombinant Human MUC20 cell lysate		N/A		Inquiry
Human	MUC20-6521HF	Recombinant Full Length Human MUC20 Protein, GST-tagged	In Vitro Cell Free System	GST	538 amino acids	Inquiry
Human	MUC20-5749H	Recombinant Human MUC20 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	Muc20-1804M	Recombinant Mouse Muc20 Protein, His-tagged	E.coli	N-His	Thr399-Asp603	Inquiry
Rat	Muc20-5711R	Recombinant Rat Muc20 protein, His & GST-tagged	E.coli	His/GST	Thr113~Asn347 (Accession # B2RZ35)	Inquiry

Involved Pathway
Protein Function
Interacting Protein

MUC20 involved in several pathways and played different roles in them. We selected most pathways MUC20 participated on our site, such as Metabolism of proteins, O-linked glycosylation, O-linked glycosylation of mucins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUC20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Metabolism of proteins	LMCD1;ADAMTS4;TBCB;SCFD1;HDGF;CGB5;SLC35A1;MPDU1B;GRPEL2
O-linked glycosylation	MUC5AC;ADAMTS10;MUC12;ADAMTSL3;ADAMTS3;GALNT5;B3GNT8;SPON1B;B3GALTL
O-linked glycosylation of mucins	MUC13;B3GNT2A;ST6GALNAC2;GCNT3;MUC1;MUC20;GALNTL2;GALNT6;A4GNT
Post-translational protein modification	GALNT13;ARSD;DNAJC24;MPDU1A;MCFD2;SPON2;ADAMTS18;NAPG;MPDU1
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	DEPDC6;MUC20
Termination of O-glycan biosynthesis	MUC4;MUC13;MUC20;MUC15;MUC1;MUC21;MUCL1;MUC5AC;MUC12

MUC20 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MUC20 itself. We selected most functions MUC20 had, and list some proteins which have the same functions with MUC20. You can find most of the proteins on our site.

Function	Related Protein

MUC20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUC20 here. Most of them are supplied by our site. Hope this information will be useful for your research of MUC20.

ALDOB; ELOVL3