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Official Full Name myosin IIIA
Background The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.
Synonyms MYO3A; myosin IIIA; deafness, autosomal recessive 30 , DFNB30; myosin-IIIa; deafness, autosomal recessive 30; DFNB30
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYO3A-301341H Recombinant Human MYO3A protein, GST-tagged E.coli GST
    Human MYO3A-1160HCL Recombinant Human MYO3A cell lysate N/A
    Human MYO3A-5838H Recombinant Human MYO3A Protein, GST-tagged Wheat Germ GST
    Human MYO3A-90H Recombinant Human MYO3A, GST-tagged Sf9 Insect Cell GST
    Zebrafish MYO3A-11619Z Recombinant Zebrafish MYO3A Mammalian Cell His

    MYO3A involved in several pathways and played different roles in them. We selected most pathways MYO3A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MYO3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    MYO3A has several biochemical functions, for example, ADP binding, ATP binding, actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYO3A itself. We selected most functions MYO3A had, and list some proteins which have the same functions with MYO3A. You can find most of the proteins on our site.

    Function Related Protein
    ADP binding MYO7A; ATP1A1; APAF1; MYO9B; MIEF1; MYO18A; PKM; ACTA1; P2RY1; VCP
    ATP binding ASS1; PHKG1; ATP2B1A; EIF4A1A; RIOK2; HSP90B1; NRBP1; SPHK1; CBWD1; UBE2W
    actin filament binding CTNNA1; TULP1; FSCN2A; PLDN; ARPC1A; MAP1S; CTNNA3; WIPF2; MYL4; MYH11
    actin-dependent ATPase activity MYL6; MYH10; MYO1D; MYO1C; MYH7; MYO3A; MYO7A; MYH9
    calmodulin binding OBSCN; NRGN; CAMKK1; ADD2; DAPK1; CAMKV; PCDP1; MKNK2A; INVS; ITPKC
    microfilament motor activity MYO3A; MYH9; MYO5B; MYO1D; MYH3; MYH7; MYO3B; STRC; MYO9B; MYO7A
    plus-end directed microfilament motor activity MYO3A; MYO19
    protein kinase activity RIPK1L; CSNK2A2A; MAK; PTK2BB; MAP3K5; CHEK1; PRKCI; RIPK3; PKDCC; CDK5R1
    protein serine/threonine kinase activity PRKCA; MAPKAPK2; SBK3; PRKAA2; IRAK3; STK11; PIK3R4; SGK2; ADCK4; SPEG

    MYO3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYO3A here. Most of them are supplied by our site. Hope this information will be useful for your research of MYO3A.


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