NCKAP1
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Official Full Name
NCK-associated protein 1 -
Overview
Nck-associated protein 1 is a protein that in humans is encoded by the NCKAP1 gene. -
Synonyms
NCKAP1;NCK-associated protein 1;HEM2;Nap1;NAP125;NAP 1;p125Nap1;membrane-associated protein HEM-2;MGC8981;FLJ11291;KIAA0587
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NCKAP1-1176H | Recombinant Human NCKAP1, GST-tagged | E.coli | Human | GST | C-term-350aa | |
| NCKAP1-2957R | Recombinant Rhesus monkey NCKAP1 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| NCKAP1-3921R | Recombinant Rat NCKAP1 Protein | Mammalian Cells | Rat | His |
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| NCKAP1-7223Z | Recombinant Zebrafish NCKAP1 | Mammalian Cells | Zebrafish | His |
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| NCKAP1-3944HCL | Recombinant Human NCKAP1 293 Cell Lysate | HEK293 | Human | Non |
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| NCKAP1-2776R | Recombinant Rhesus Macaque NCKAP1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| NCKAP1-2776R-B | Recombinant Rhesus Macaque NCKAP1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| NCKAP1-3579R | Recombinant Rat NCKAP1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| NCKAP1-3579R-B | Recombinant Rat NCKAP1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
NCKAP1 involved in several pathways and played different roles in them. We selected most pathways NCKAP1 participated on our site, such as Diurnally regulated genes with circadian orthologs,E-cadherin signaling in the nascent adherens junction,ErbB1 downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCKAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RHO GTPase Effectors | DIAPH1,CCDC99,ROPN1,NOXA1,NF2A,MIS12,NUF2,KNTC1,CDCA8,RHOAE |
| Innate Immune System | PELI3,TXNIPB,MYO1C,S100A12,BTR02,ABI1A,WIPF2,UNC93B1,DUSP3B,C1rb |
| ErbB1 downstream signaling | ARF4,EGR1,ABI1,WASF2,ACTR3,CHN2,MAP3K2,ACTR2,BAIAP2,EPS8 |
| E-cadherin signaling in the nascent adherens junction | KLHL20,WASF2,CTNND1,ABI1 |
| RAC1 signaling pathway | RACGAP1,ABI2,BAIAP2,NOXA1,NOXO1,ABI1,IQGAP3 |
| Immune System | EDA,EIF4G2A,ASB13,ARIH2,RAPGEF3,EVL,GBP4,Siglece,ATG7,CLEC2D |
| Fcgamma receptor (FCGR) dependent phagocytosis | ABI1,ABI2,ACTR2,ACTR3,MYO1C,WIPF3,IgG3,PLD4,PPAPDC1B,ARPC1A |
| Diurnally regulated genes with circadian orthologs | ZFR,STBD1,PURA,CRY1,ERC2,QK,KLF9,EIF4G2,RBPMS,ITM2B |
Protein Function
NCKAP1 has several biochemical functions, for example, contributes_to Rac GTPase binding,protein binding,protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCKAP1 itself. We selected most functions NCKAP1 had, and list some proteins which have the same functions with NCKAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to Rac GTPase binding | BRK1,WASF1,CYFIP1,ABI2 |
| protein binding | GAPDHS,ARL14,ACTB,MCM3,MMP14,KAL1,EPC1,CDK9,FIP1L1,C6orf130 |
| protein complex binding | BAG3,ABI1,NDUFA9,TUB,AP2A2,TULP3,FBN1,GIT2,RNF40,BAX |
Interacting Protein
NCKAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCKAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCKAP1.
ABI1;YWHAB;ABI2;CYFIP1;GAS7
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