NEK11
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Official Full Name
NIMA (never in mitosis gene a)- related kinase 11
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Overview
This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described. -
Synonyms
NEK11; NIMA (never in mitosis gene a)- related kinase 11; serine/threonine-protein kinase Nek11; FLJ23495;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cynomolgus Monkey
- Human
- Human
- Mouse
- HEK293
- HEK293T
- Insect (sf21)
- Insect Cell
- Mammalian Cell
- Sf21
- Sf9 Insect Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
NEK11 involved in several pathways and played different roles in them. We selected most pathways NEK11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NEK11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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NEK11 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEK11 itself. We selected most functions NEK11 had, and list some proteins which have the same functions with NEK11. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | UCKL1;IKBKB;MARK3;CKMB;EPHB2B;NSF;SIK2A;CDK9;AK5L |
metal ion binding | CYBA;GLI4;ZNF202;ZFP110;ZIK1;ATP1A1A.3;PVALB3;HBAE1;NDUFS1 |
protein binding | CHCHD2;INPP5D;PCP4;MARCKSL1;CASP14;GLA;AK3;SPEG;DZIP1 |
protein serine/threonine kinase activity | ROCK1;ACVR1L;PAK1;SBK1;PDPK1;VRK1;DAPK2;SGK1;ARAF |
NEK11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEK11 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEK11.
NEK2; HSP90AB1; NEK2; MYC; linkable pd173955 analogue; linkable sunitinib analogue; bosutinib; imatinib; dasatinib
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