NLGN3

  • Official Full Name

    neuroligin 3

  • Overview

    This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    NLGN3; neuroligin 3; neuroligin-3; ASPGX1; AUTSX1; HNL3; KIAA1480; Gliotactin homolog; OTTHUMP00000023498; OTTHUMP00000023499; OTTHUMP00000023500;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NLGN3-3881H Recombinant Human NLGN3 protein, His-tagged HEK293 His Gln38-Ser689
Human NLGN3-46H Recombinant Human NLGN3 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NLGN3-2082HCL Recombinant Human NLGN3 cell lysate Human Cell N/A
Human NLGN3-393H Recombinant Human NLGN3 Protein, His-tagged HEK293 His 848
Human NLGN3-5911H Recombinant Human NLGN3 Protein, GST-tagged Wheat Germ GST
Human NLGN3-1393HFL Recombinant Full Length Human NLGN3 protein, Flag-tagged Mamanlian cells Flag
Human NLGN3-2490H Recombinant Human NLGN3 Protein, His-tagged E.coli N-His Pro40-Ile289
Human NLGN3-0275H Recombinant Human NLGN3 protein, His-tagged HEK293 His Met1-Ser689
Human NLGN3-6712HF Recombinant Full Length Human NLGN3 Protein, GST-tagged In Vitro Cell Free System GST 828 amino acids
Mouse NLGN3-10710M Recombinant Mouse NLGN3 Protein Mammalian Cell His
Mouse NLGN3-6090M Recombinant Mouse NLGN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nlgn3-4431M Recombinant Mouse Nlgn3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NLGN3-6090M-B Recombinant Mouse NLGN3 Protein Pre-coupled Magnetic Beads HEK293
Rat NLGN3-3997R Recombinant Rat NLGN3 Protein Mammalian Cell His
Rat NLGN3-3656R Recombinant Rat NLGN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NLGN3-3656R-B Recombinant Rat NLGN3 Protein Pre-coupled Magnetic Beads HEK293
Chicken NLGN3-4070C Recombinant Chicken NLGN3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

NLGN3 involved in several pathways and played different roles in them. We selected most pathways NLGN3 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with NLGN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)CLDN4;ITGB1A;NRCAMA;BF2;MHC2DCB;F11R.1;PDCD1LG2;JAM3;HLA-DPB1

NLGN3 has several biochemical functions, for example, cell adhesion molecule binding, NOT cholinesterase activity, neurexin family protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NLGN3 itself. We selected most functions NLGN3 had, and list some proteins which have the same functions with NLGN3. You can find most of the proteins on our site.

Function Related Protein
cell adhesion molecule bindingCADM1;PVR;POSTNB;AMICA1;DSP;SDCBP;CADM1A;POSTN;NLGN4X
NOT cholinesterase activityNLGN4Y;NLGN1;NLGN2;NLGN2A;NLGN4A;NLGN3A;NLGN3B;NLGN2B;NLGN3
neurexin family protein bindingNLGN4B;SDCBP;NLGN4A;SYTL2;SYTL1;NLGN3B;CASK;LRRTM2;NLGN3A
protein bindingSPRR2E;PPFIA1;ILVBL;RAB5C;ITGA1;ADIPOQ;COPS5;POC1A;ZNF593
receptor activityJMJD6;NLGN2A;CD46;VMN1R47;Pla2r1;PLAUR;SMAGP;MED1;ITGB4
scaffold protein bindingNLGN1;CACNA1G;IKBKB;MAP2K2;DSP;NLRP1;SCN5A;CRIPT;HOMER1

NLGN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLGN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLGN3.

TGFBR1; PRDX2

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