NRIP1

  • Official Full Name

    nuclear receptor interacting protein 1

  • Overview

    Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]

  • Synonyms

    NRIP1;nuclear receptor interacting protein 1;RIP140;nuclear receptor-interacting protein 1;nuclear factor RIP140;receptor interacting protein 140;receptor-interacting protein 140
Cat.# Product name Source (Host) Species Tag Protein Length Price
NRIP1-10890M Recombinant Mouse NRIP1 Protein Mammalian Cells Mouse His
NRIP1-3695HCL Recombinant Human NRIP1 293 Cell Lysate HEK293 Human Non
NRIP1-6202M Recombinant Mouse NRIP1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
NRIP1-6202M-B Recombinant Mouse NRIP1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NRIP1 involved in several pathways and played different roles in them. We selected most pathways NRIP1 participated on our site, such as Adipogenesis,BMAL1:CLOCK,NPAS2 activates circadian gene expression,Circadian Clock, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Retinoic acid receptors-mediated signaling RBP1
    Adipogenesis RETN,MBNL1,EPAS1B,SPOCK1,MIXL1,GATA2A,FOXC2,EBF1,GADD45A,AGT
    Circadian Clock CRY2,CARM1,CSNK1E,CRY1,RAI1,DBP,NAMPT,CPT1A,HELZ2
    Ovarian Infertility Genes SYNE2,GJA4,ZP2,INHA,NR5A1,DMC1,MSH5,DAZL,ZP3
    Coregulation of Androgen receptor activity PAWR,KDM3A,CMTM2A,TCF4,CTDSP2,ZMIZ1,SNURF,MAK,CMTM2,KDM4C
    FOXA1 transcription factor network CYP2C18,DSCAM,NR2F2,TFF1,FOXA1,NFIC,NFIB,CC10,CEBPB,NFIA
    BMAL1:CLOCK,NPAS2 activates circadian gene expression CRY2,DBP,NAMPT,NCOA2,HELZ2,CARM1,CRY1,CREBBP

    Protein Function

    NRIP1 has several biochemical functions, for example, androgen receptor binding,core promoter sequence-specific DNA binding,estrogen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRIP1 itself. We selected most functions NRIP1 had, and list some proteins which have the same functions with NRIP1. You can find most of the proteins on our site.

    Function Related Protein
    core promoter sequence-specific DNA binding PDX1,TRP53,NR1D1,SOX1,PPARG,TP53,SOX9,H2AFY,NRF1,MYOCD
    transcription coactivator activity TAF5L,ESR2,GMEB2,IL31RA,TFDP1A,TADA1,PSMD9,CITED2,LPIN3,TADA2A
    nuclear hormone receptor binding TACC2,CTNNB1,HIF1A,NCOA2,MED1,Ankar,TCF7L2,BUD31,NCOA1,SNW1
    histone deacetylase binding D7ERTD443E,PKN2,CEBPA,HDAC1,GMNN,PKN1,RUNX2,MEF2D,BRMS1LA,SOD3
    androgen receptor binding BRCA1,PARK7,PRKCB,EP300,PIAS2,FOXH1,CCNE1,CALR,PIAS1,NCOA1
    estrogen receptor binding FUS,PPARG,PRMT2,CCDC62,XBP1,DDX5,ARRB1,LEF1,NCOA1,HSD17B10
    glucocorticoid receptor binding CEBPB,ETS2,STAT5B,EP300,STAT3,GRIP1,NR4A2,FKBP4,YWHAH
    transcription corepressor activity DMAP1,LMCD1,ATN1,E2F8,ZNF274,TRIB3,PROX1,C1QBP,LIMD1,SSX5
    protein binding MYOM1,NITR9,CARHSP1,CAMTA2,HDAC7,RPLP0,LIN7A,MEIOB,GRIN2A,PRADC1

    Interacting Protein

    NRIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NRIP1.

    RARA;FHL1;LDOC1;CEP70;PRMT1

    Resources

    References

    • Campo, GM; Avenoso, A; et al. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:201-208(2015).
    • Pisetsky, DS; et al. The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. AUTOIMMUNITY 47:487-493(2014).

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