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NRIP1

  • Official Full Name

    nuclear receptor interacting protein 1

  • Overview

    Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]
  • Synonyms

    NRIP1; nuclear receptor interacting protein 1; RIP140; nuclear receptor-interacting protein 1; nuclear factor RIP140; receptor interacting protein 140; receptor-interacting protein 140;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NRIP1-3695HCL Recombinant Human NRIP1 293 Cell Lysate HEK293 N/A
Mouse NRIP1-10890M Recombinant Mouse NRIP1 Protein Mammalian Cell His
Mouse NRIP1-6202M-B Recombinant Mouse NRIP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse NRIP1-6202M Recombinant Mouse NRIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NRIP1 Related Articles

NRIP1 involved in several pathways and played different roles in them. We selected most pathways NRIP1 participated on our site, such as Adipogenesis, BMAL1:CLOCK,NPAS2 activates circadian gene expression, Circadian Clock, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AdipogenesisMEF2B;CDKN1A;GADD45A;CFD;BMP3;AGPAT2;PLIN2;CNTFR;MEF2AA
BMAL1:CLOCK,NPAS2 activates circadian gene expressionCREBBP;DBP;NAMPT;CRY2;NCOA2;CARM1;HELZ2;NRIP1;CRY1
Circadian ClockNRIP1;CARM1;CRY2;NAMPT;RAI1;CSNK1E;DBP;HELZ2;CPT1A
Coregulation of Androgen receptor activityCMTM2;TMF1;TCF4;SNURF;KDM4C;CARM1;ZMIZ1;KDM3A;TGFB1I1
FOXA1 transcription factor networkTFF1;NRIP1;NR2F2;CEBPB;CYP2C18;DSCAM;NFIC;FOXA1;CC10
Ovarian Infertility GenesZP3;DMC1;ZP2;NRIP1;MSH5;INHA;DAZL;NR5A1;GJA4
RORA activates gene expression
Retinoic acid receptors-mediated signalingNRIP1;RBP1

NRIP1 has several biochemical functions, for example, androgen receptor binding, core promoter sequence-specific DNA binding, estrogen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRIP1 itself. We selected most functions NRIP1 had, and list some proteins which have the same functions with NRIP1. You can find most of the proteins on our site.

Function Related Protein
androgen receptor bindingKAT5;RNF14;PIAS1;CDK7;PIAS2;PRMT2;CALR;RNF4;KDM4C
core promoter sequence-specific DNA bindingATF4;MYOCD;THRAP3;SOX4;PDX1;H2AFY;KLF10;MEOX1;NFYA
estrogen receptor bindingPPARGC1B;NSD1;TRIP4;DDX5;CTNNB1;DDX17;DDX54;LEF1;HSD17B10
glucocorticoid receptor bindingGRIP1;EP300;FKBP4;CEBPB;NRIP1;YWHAH;NR4A2;ETS2;STAT5B
histone deacetylase bindingSKOR2;XBP1;ZFP932;HEY2;WDTC1;HES1;MEF2D;TOP2A;NKX2-5
nuclear hormone receptor bindingMED1;TACC2;ACTN4;Ankar;NRIP1;NCOR1;NCOA3;CTNNB1;CRY1
protein bindingUBA6;SATB1;MPZL3;CALCOCO2;SEPT10;UBQLN4;GSG1L;PRAC;STRA13
retinoid X receptor bindingNR1H4;NRIP1;RARB;PPARG;NR0B2;MED25;VDR;HMGA1-RS1;HMGA1
transcription coactivator activityNEUROD1;SCAND1;ESR2;YY1;BCL10;GTF2A1;JUNBB;SNW1;FHL2
transcription corepressor activityPBXIP1;ZFPM2;MXD4;E4F1;SNW1;EID1;TRIM28;NR0B2;SFMBT1

NRIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NRIP1.

RARA; FHL1; LDOC1; CEP70; PRMT1

Campo, GM; Avenoso, A; et al. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:201-208(2015).
Pisetsky, DS; et al. The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. AUTOIMMUNITY 47:487-493(2014).
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