NUAK1
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Official Full Name
NUAK family, SNF1-like kinase, 1
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Overview
AMP-activated protein kinases (AMPKs) constitute a serine/threonine protein kinase family, which is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPKalpha1, AMPKalpha2, MELK and SNARK are -
Synonyms
NUAK1; NUAK family, SNF1-like kinase, 1; NUAK family SNF1-like kinase 1; AMP activated protein kinase family member 5; ARK5; KIAA0537; omphalocele kinase 1; AMPK-related protein kinase 5; AMP-activated protein kinase family member 5;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Human
- Mouse
- E.coli
- HEK293
- Insect (sf21)
- Insect Cell
- Mammalian Cell
- Sf21
- Sf9 Insect Cell
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
- No tag
- Involved Pathway
- Protein Function
- Interacting Protein
NUAK1 involved in several pathways and played different roles in them. We selected most pathways NUAK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NUAK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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NUAK1 has several biochemical functions, for example, ATP binding, metal ion binding, p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUAK1 itself. We selected most functions NUAK1 had, and list some proteins which have the same functions with NUAK1. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | SUCLA2;MSH4;PAPSS2;ATM;OAS2;PEX6;HNRNPU;MADD;ABCC8 |
metal ion binding | ARL1;GDPD4;TSHZ3;KCND1;ECEL1;DNAJA2;CRBN;DMRTA1;ACLY |
p53 binding | ANKRD1;MDM2;AXIN1;TP53BP1;EHMT1;PSME3;ZFP346;NUAK1;CREBBP |
protein binding | TIMP2;SNRPD3;FGFR1;BOC;PLEK;VCAN;ELK1;TNIP3;IYD |
protein serine/threonine kinase activity | SIK2;STK31;cka1;MAPK14;PDK3;GRK7B;TAF1;PRKACAB;RPS6KA1 |
NUAK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUAK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUAK1.
TP53; STK11; 27764561; LATS1; IGHA2; S100A8; S100A9; PRKAR1A; PRPSAP1; USP9X; SRRM2; midostaurin; crizotinib; cdkn1a_human_gene
- Q&As
- Reviews
Q&As (5)
Ask a questionMutations in the NUAK1 gene have been identified in certain cancers and may have implications for prognosis and treatment response.
Yes, several preclinical studies have identified potential drug candidates that target NUAK1 protein for cancer therapy.
NUAK1 protein has been shown to regulate stress responses in cells, including responses to oxidative stress and DNA damage.
Potential side effects may include off-target effects on other cellular processes and toxicity to normal cells.
Targeting NUAK1 protein may have implications for conditions related to stress responses, such as neurodegenerative diseases and aging-related disorders.
Customer Reviews (3)
Write a reviewThe NUAK1 protein is an exceptional product that meets the highest standards of quality, making it an ideal choice to fulfill my experimental requirements.
By incorporating the NUAK1 protein into electron microscopy studies, researchers gain insights into the intricate three-dimensional architecture of proteins, facilitating a deeper comprehension of their functions and aiding in the development of novel therapeutics.
Its reliability and effectiveness in generating accurate data make it an indispensable resource, driving scientific exploration and advancing our understanding of protein structure and function
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