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OPA3

  • Official Full Name

    optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

  • Overview

    The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    OPA3; optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia); optic atrophy 3 protein; FLJ22187; MGA3; FLJ25932; Iraqi Jewish optic atrophy plus (3 methylglutaconicaciduria type 3); MGC75494; OPA 3; OPA3 protein; Optic atrophy 3 (Iraqi Jewish optic atrophy plus); Optic atrophy 3; Optic atrophy 3 (Iraqi-Jewish optic atrophy plus);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human OPA3-1460H Recombinant Human OPA3, His-tagged E.coli His 24-179aa
Human OPA3-3575HCL Recombinant Human OPA3 293 Cell Lysate HEK293 N/A
Human OPA3-2101HFL Recombinant Full Length Human OPA3 Protein, C-Flag-tagged Mammalian cells Flag
Human OPA3-1581H Recombinant Human OPA3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human OPA3-1581H-B Recombinant Human OPA3 Protein Pre-coupled Magnetic Beads HEK293
Mouse OPA3-12163M Recombinant Mouse OPA3 Protein Mammalian Cell His
Mouse Opa3-8011M Recombinant Mouse Opa3 protein, His & T7-tagged E.coli His/T7 Leu11~Lys179 (Accession # Q505D7)
Mouse OPA3-6396M-B Recombinant Mouse OPA3 Protein Pre-coupled Magnetic Beads HEK293
Mouse OPA3-6396M Recombinant Mouse OPA3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Opa3-8012R Recombinant Rat Opa3 protein, His & T7-tagged E.coli His/T7 Met1~Thr200 (Accession # B5DF67)
Rhesus Macaque OPA3-3168R Recombinant Rhesus monkey OPA3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque OPA3-2986R-B Recombinant Rhesus Macaque OPA3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque OPA3-2986R Recombinant Rhesus Macaque OPA3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish OPA3-5025Z Recombinant Zebrafish OPA3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • OPA3 Related Articles

OPA3 involved in several pathways and played different roles in them. We selected most pathways OPA3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OPA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

OPA3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by OPA3 itself. We selected most functions OPA3 had, and list some proteins which have the same functions with OPA3. You can find most of the proteins on our site.

Function Related Protein

OPA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPA3.

SUV39H1; KDM1A; PRMT6

Sergouniotis, PI; Perveen, R; et al. Clinical and molecular genetic findings in autosomal dominant OPA3-related optic neuropathy. NEUROGENETICS 16:69-75(2015).
Yahalom, G; Anikster, Y; et al. Costeff syndrome: clinical features and natural history. JOURNAL OF NEUROLOGY 261:2275-2282(2014).
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