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P2RX5

Official Full Name

purinergic receptor P2X, ligand-gated ion channel, 5
Overview

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3).
Synonyms

P2RX5; purinergic receptor P2X, ligand-gated ion channel, 5; P2X purinoceptor 5; P2X5; ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; MGC47755; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; OTTHUMP00000115870; OTTHUMP00000241718; OTTHUMP00000241719; OTTHUMP00000241720; OTTHUMP00000241722; OTTHUMP00000241723; lymphoid-restricted histocompatibility antigen-1; LRH-1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	P2RX5-1492H	Recombinant Human P2RX5, GST-tagged	E.coli	GST	52-422aa	$319 / 25ug
Human	P2RX5-3497HCL	Recombinant Human P2RX5 293 Cell Lysate	HEK293	N/A		Inquiry
Human	P2RX5-3498HCL	Recombinant Human P2RX5 293 Cell Lysate	HEK293	N/A		Inquiry
Human	P2RX5-2538H	Recombinant Human P2RX5 Protein, His-tagged	E.coli	N-His	Lys52-Arg319	Inquiry
Rat	P2RX5-4230R	Recombinant Rat P2RX5 Protein	Mammalian Cell	His		Inquiry
Rat	P2RX5-3892R	Recombinant Rat P2RX5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	P2RX5-3892R-B	Recombinant Rat P2RX5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	P2RX5-9763Z	Recombinant Zebrafish P2RX5	Mammalian Cell	His		Inquiry
Chicken	P2RX5-6313C	Recombinant Chicken P2RX5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

P2RX5 involved in several pathways and played different roles in them. We selected most pathways P2RX5 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Calcium signaling pathway	PLCD3A;CALM2B;PHKG1;CHRNA7;ADRB2A;STIM2;PHKG1A;SLC8A1B;ERBB3B
Neuroactive ligand-receptor interaction	P2RX7;GABRA2;GRIA3B;AGTR1B;TSHB;CHRNA4;LEPB;GRIN2A;F2

P2RX5 has several biochemical functions, for example, ATP binding, extracellular ATP-gated cation channel activity, ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX5 itself. We selected most functions P2RX5 had, and list some proteins which have the same functions with P2RX5. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	ATP13A3;KIF6;ADK;ATP2A2B;NME2B.2;HIPK3A;WRNIP1;MYH11A;LATS1
extracellular ATP-gated cation channel activity	P2RX3B;P2RX2;P2RX4;P2RX7;P2RX8;P2RX3;P2RX6;NNR;P2RX4A
ion channel activity	KCNA6A;TRPC5A;TRPA1A;CHRNA1;KCNS3B;KCNH5A;TRPV2;P2RX3B;P2RX5
purinergic nucleotide receptor activity	P2RX2;P2RX1;P2RX3;P2RX3B;P2RX4B;P2RX4;P2RX4A;P2RX3A;P2RX8
transmembrane signaling receptor activity	P2RX5;Cd79a, Cd79b;TLR9;GHRHR2;CELSR1;TLR1;TLR6;GPR113;OR12D3

P2RX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX5.

thrC