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PAIP1

Official Full Name

poly(A) binding protein interacting protein 1
Overview

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Synonyms

PAIP1; poly(A) binding protein interacting protein 1; polyadenylate-binding protein-interacting protein 1; PAIP-1; PABP-interacting protein 1; PABC1-interacting protein 1; poly(A)-binding protein-interacting protein 1; polyadenylate binding protein-intera;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PAIP1-1512H	Recombinant Human PAIP1, GST-tagged	E.coli	GST	C-term-300aa	$319 / 25ug
Human	PAIP1-3460HCL	Recombinant Human PAIP1 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	Paip1-4661M	Recombinant Mouse Paip1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rhesus Macaque	PAIP1-3287R	Recombinant Rhesus monkey PAIP1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	PAIP1-3105R-B	Recombinant Rhesus Macaque PAIP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	PAIP1-3105R	Recombinant Rhesus Macaque PAIP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	PAIP1-945Z	Recombinant Zebrafish PAIP1	Mammalian Cell	His		Inquiry
Chicken	PAIP1-5425C	Recombinant Chicken PAIP1	Mammalian Cell	His		Inquiry
Chicken	PAIP1-5426C	Recombinant Chicken PAIP1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PAIP1 Related Articles

PAIP1 involved in several pathways and played different roles in them. We selected most pathways PAIP1 participated on our site, such as Deadenylation of mRNA, Deadenylation-dependent mRNA decay, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Deadenylation of mRNA	PAIP1;EIF4EB;TNKS1BP1;EIF4B;EIF4E;EIF4A2;D1BWG0212E;EIF4G1;EIF4A1
Deadenylation-dependent mRNA decay	DDX6;EIF4EB;DCP2;EIF4E;TNKS1BP1;EIF4G1;DCP1B;EIF4A2;PAIP1
Gene Expression	ZNF333;DNMT3B;TRMT12;BAZ2A;MBD3;ZNF549;ZNF200;ZNF471;ZNF561
RNA transport	SUMO3B;SMN;RBM8A;NXT2;EEF1A1B;TGS1;TRNT1;POP7;NCBP1
Translation Factors	PAIP1;EIF4EBP2;EEF1G;EIF2B1;EEF2B;EIF5A;EEF1B2;EEF1D;EIF1

PAIP1 has several biochemical functions, for example, RNA binding, protein binding, translation activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAIP1 itself. We selected most functions PAIP1 had, and list some proteins which have the same functions with PAIP1. You can find most of the proteins on our site.

Function	Related Protein
RNA binding	EXOSC3;PPP1R8;RAVER1;GTF3A;MIF4GDB;EIF2S2;PABPC1L2A;DDX51;PATL1
protein binding	RIPK3;EMD;AHSA2;FZD8;SAP30L;MOCOS;KAT2B;SNX19;RGMA
translation activator activity	PABPC1;LARP1;DAZL;RPS27L;ABCF1;BOLL;PAIP1

PAIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAIP1.

PABPC1; Pabpc1; Eif4a1

Taleat, Z; Cristea, C; et al. Electrochemical immunoassay based on aptamer-protein interaction and functionalized polymer for cancer biomarker detection. JOURNAL OF ELECTROANALYTICAL CHEMISTRY 717:119-124(2014).

Bergeron, D; Lapointe, C; et al. An Out-of-frame Overlapping Reading Frame in the Ataxin-1 Coding Sequence Encodes a Novel Ataxin-1 Interacting Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 288:-(2013).