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PALB2

  • Official Full Name

    partner and localizer of BRCA2

  • Overview

    This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008]
  • Synonyms

    PALB2; partner and localizer of BRCA2; FANCN; PNCA3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PALB2-1516H Recombinant Human PALB2, GST-tagged E.coli GST 841-1186aa
Human PALB2-3451HCL Recombinant Human PALB2 293 Cell Lysate HEK293 N/A
Human PALB2-37H Recombinant Human PALB2 Protein, His-tagged E.coli His
Mouse PALB2-12324M Recombinant Mouse PALB2 Protein Mammalian Cell His
Mouse PALB2-6477M-B Recombinant Mouse PALB2 Protein Pre-coupled Magnetic Beads HEK293
Mouse PALB2-6477M Recombinant Mouse PALB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PALB2 involved in several pathways and played different roles in them. We selected most pathways PALB2 participated on our site, such as Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PALB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fanconi anemia pathwayRAD51C;FANCI;PMS2;PALB2;WDR48;POLH;APITD1;ATRIP;RPA1

PALB2 has several biochemical functions, for example, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PALB2 itself. We selected most functions PALB2 had, and list some proteins which have the same functions with PALB2. You can find most of the proteins on our site.

Function Related Protein
DNA bindingTERT;HIST1H2B5;PPARA;TSNAX;ZNF280A;NR5A5;JRKL;THAP11;TIGD2
protein bindingGLI1;APOBEC1;FATE1;ALKBH6;MT1A;PLSCR1;TIMM9;STX7;HMGB1

PALB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PALB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PALB2.

BRCA2; POLH

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