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PANK3

Official Full Name

pantothenate kinase 3
Overview

This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.
Synonyms

PANK3; pantothenate kinase 3; FLJ12899; hPanK3; pantothenic acid kinase 3; MGC16863; DKFZp686O22247;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PANK3-29H	Recombinant Human PANK3, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	PANK3-1521H	Recombinant Human PANK3, GST-tagged	E.coli	GST	C-term-312aa	$319 / 25ug
Human	PANK3-3444HCL	Recombinant Human PANK3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PANK3-2127H	Recombinant Human PANK3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Pank3-4670M	Recombinant Mouse Pank3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PANK3 Related Articles

PANK3 involved in several pathways and played different roles in them. We selected most pathways PANK3 participated on our site, such as Pantothenate and CoA biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PANK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Pantothenate and CoA biosynthesis	UPB1;BCAT1;PANK4;PANK2;PANK1;BCAT2;PPCS;DPYS;PANK3
Metabolic pathways	PIK3C2B;PIGN;GBGT1L4;COX8A;POLR1B;POLD4;SGMS2;HAL;MECR

PANK3 has several biochemical functions, for example, ATP binding, pantothenate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PANK3 itself. We selected most functions PANK3 had, and list some proteins which have the same functions with PANK3. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	CDK1;CDC6;PIP4K2B;CDC34B;KATNAL2;MAP2K2A;STK24;ATP6V1AA;MAPK7
pantothenate kinase activity	PANK1B;PANK2;PANK3;PANK4;PANK1

PANK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PANK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PANK3.

Li, MH; Liu, ZJ; et al. miR-103 promotes 3T3-L1 cell adipogenesis through AKT/mTOR signal pathway with its target being MEF2D. BIOLOGICAL CHEMISTRY 396:235-244(2015).

Dwarakanath, S; Zafar, A; et al. Does lesioning surgery have a role in the management of multietiological tremor in the era of Deep Brain Stimulation?. CLINICAL NEUROLOGY AND NEUROSURGERY 125:131-136(2014).