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PAX1

Official Full Name

paired box 1
Overview

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically;contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development.;This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral;column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene.;Mutations in this gene are also associated with vertebral malformations.
Synonyms

PAX1; paired box 1; paired box gene 1; paired box protein Pax-1; HUP48; OTTHUMP00000030407; Paired box protein Pax 1; Paired domain gene HuP48; PAX 1; PAX1_HUMAN; OTTHUMP00000206906;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	PAX1-316H	Recombinant Human PAX1	Mammalian Cell	His	Inquiry
Human	PAX1-3799H-B	Recombinant Human PAX1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Human	PAX1-3799H	Recombinant Human PAX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	PAX1-12390M	Recombinant Mouse PAX1 Protein	Mammalian Cell	His	Inquiry
Mouse	PAX1-6515M	Recombinant Mouse PAX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	PAX1-6515M-B	Recombinant Mouse PAX1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PAX1 involved in several pathways and played different roles in them. We selected most pathways PAX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PAX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PAX1 has several biochemical functions, for example, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAX1 itself. We selected most functions PAX1 had, and list some proteins which have the same functions with PAX1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	HNF4A;IRF3;ZFP36L3;POU2AF1;TADA2A;MAP3K7;HOXC12B;NFYA;ZNF8

PAX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAX1.