PCCB
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Official Full Name
propionyl CoA carboxylase, beta polypeptide
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Overview
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PCCB; propionyl CoA carboxylase, beta polypeptide; propionyl Coenzyme A carboxylase, beta polypeptide; propionyl-CoA carboxylase beta chain, mitochondrial; mitochondrial; PCCase subunit beta; PCCB_HUMAN; pccBC Complementation group; Propanoyl CoA:carbon dioxide ligase subunit beta; Propanoyl-CoA:carbon dioxide ligase subunit beta; Propionyl CoA carboxylase beta chain, mitochondrial; Propionyl-CoA carboxylase , beta subunit; Propionyl-CoA carboxylase beta chain; R74805;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | PCCB-1550H | Recombinant Human PCCB, GST-tagged | E.coli | GST | C-term-300aa | |
Human | PCCB-1291HCL | Recombinant Human PCCB cell lysate | N/A | |||
Human | PCCB-2553H | Recombinant Human PCCB Protein, His-tagged | E.coli | N-His | Glu309-His534 | |
Mouse | PCCB-12417M | Recombinant Mouse PCCB Protein | Mammalian Cell | His | ||
Mouse | Pccb-8177M | Recombinant Mouse Pccb protein, His & T7-tagged | E.coli | His/T7 | Glu311~Leu541 (Accession # Q7TMF4) | |
Mouse | PCCB-6535M-B | Recombinant Mouse PCCB Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | PCCB-6535M | Recombinant Mouse PCCB Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | PCCB-3318R | Recombinant Rhesus monkey PCCB Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | PCCB-3136R | Recombinant Rhesus Macaque PCCB Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | PCCB-3136R-B | Recombinant Rhesus Macaque PCCB Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | PCCB-12178Z | Recombinant Zebrafish PCCB | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- PCCB Related Articles
PCCB involved in several pathways and played different roles in them. We selected most pathways PCCB participated on our site, such as Valine, leucine and isoleucine degradation, Glyoxylate and dicarboxylate metabolism, Propanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Valine, leucine and isoleucine degradation | ALDH9A1;HADHAB;HADHAA;BCAT2;HIBADHB;ALDH9A1B;ALDH3A2A;MCCC1;ALDH9A1A.1 |
Glyoxylate and dicarboxylate metabolism | GLULC;AMT;SHMT2;HYI;SHMT1;PCCB;HAO2;ACAT1;GRHPRA |
Propanoate metabolism | SUCLG2;HADHAB;LDHAL6A;MUT;MCEE;ACSS2;MLYCD;LDHB;ACADM |
Metabolic pathways | ALPI.1;ANPEPB;PLCH1;UMPS;AGMAT;B3GNT2B;HPGDS;ATP5D;MGAT3 |
Carbon metabolism | HADHAA;FBP1;GOT2A;PDHA1;PRPS1A;FH;ACO2;GLDC;RPE |
PCCB has several biochemical functions, for example, ATP binding, propionyl-CoA carboxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PCCB itself. We selected most functions PCCB had, and list some proteins which have the same functions with PCCB. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | GRK7;ACTC1B;LYN;MERTK;HK2;EHD3;PDPK1;ITGB1BP3;SMC5 |
propionyl-CoA carboxylase activity | PCCA;PCCB |
PCCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PCCB.
CSNK2B; INPPL1; US11; IFIT1; k7_vaccw; PPP2R2B; ICT1; EBNA-LP
- Q&As
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