PDE9A Protein


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Official Full Name PDE9A phosphodiesterase 9A
Background Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3, 5monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE10 enzyme belongs to a family of PDEs that hydrolyse both cAMP and cGMP
Synonyms PDE9A; phosphodiesterase 9A; high affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A; phosphodiesterase PDE9A21; CGMP-specific 3,5-cyclic phosphodiesterase type 9; HSPDE9A2; FLJ90181
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • His/GST
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PDE9A-448H Recombinant Human Phosphodiesterase 9A, GST-tagged Insect Cell GST
    Human PDE9A-1162H Recombinant Human PDE9A, His tagged E.coli His
    Human PDE9A-1163H Recombinant Human PDE9A, His & GST tagged Insect Cell His/GST
    Human PDE9A-550H Recombinant Human PDE9A, His-tagged E.coli His
    Human PDE9A-551H Recombinant Human PDE9A, His/GST-tagged Insect Cell His/GST
    Mouse PDE9A-12566M Recombinant Mouse PDE9A Protein Mammalian Cell His
    Rat PDE9A-4336R Recombinant Rat PDE9A Protein Mammalian Cell His
    Human PDE9A-609HCL Recombinant Human PDE9A cell lysate Insect Cell N/A
    Human PDE9A-043H Recombinant Human PDE9A Protein, His/GST-tagged Insect cell His/GST
    Mouse Pde9a-1493M Recombinant Mouse Pde9a protein, His-tagged E.coli His
    Human PDE9A-2568H Recombinant Human PDE9A Protein, His-tagged E.coli N-His
    Human PDE9A-08H Recombinant Human PDE9A Protein, His/GST-tagged Insect Cell His/GST
    Human PDE9A-3344H Recombinant Human PDE9A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PDE9A-6347H Recombinant Human PDE9A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PDE9A-741H Recombinant Human PDE9A Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human PDE9A-921H Recombinant Human PDE9A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Pde9a-4753M Recombinant Mouse Pde9a Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Kit-1849 PDE9A Assay Kit N/A

    PDE9A involved in several pathways and played different roles in them. We selected most pathways PDE9A participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE9A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism PDE7A; POLR3C; ENTPD5; POLE; POLR2F; TWISTNB; PNP; NT5C3A; NME3; PDE3A

    PDE9A has several biochemical functions, for example, 3,5-cyclic-GMP phosphodiesterase activity, 3,5-cyclic-nucleotide phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE9A itself. We selected most functions PDE9A had, and list some proteins which have the same functions with PDE9A. You can find most of the proteins on our site.

    Function Related Protein
    3,5-cyclic-GMP phosphodiesterase activity PDE6B; PDE10A; PDE6C; PDE6G; PDE9A; PDE11A; PDE6H; PDE6A; PDE5A
    3,5-cyclic-nucleotide phosphodiesterase activity PDE10A; PDE6D; PDE5AB; PDE9A; PDE4D; PDE8B; PDE11A; PDE8A; PDE5A; PDE3B
    metal ion binding COL9A1; ESRRGA; SUMF2; CAR5A; SCRT1A; ZBTB12; AOC1; ACY3.2; CYP8B1; NUPL2
    protein binding SH2B3; STX4A; PHF23; CDC37; PRPF6; TTC6; ING5; CSNK1A1; DOCK10; HIP1

    PDE9A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE9A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE9A.

    TRIM32; C9orf106; BAG3; LMO2; CLK1

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