PDE9A

  • Official Full Name

    PDE9A phosphodiesterase 9A

  • Overview

    Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3, 5monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE10 enzyme belongs to a family of PDEs that hydrolyse both cAMP and cGMP
  • Synonyms

    PDE9A; phosphodiesterase 9A; high affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A; phosphodiesterase PDE9A21; CGMP-specific 3,5-cyclic phosphodiesterase type 9; HSPDE9A2; FLJ90181;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Insect cell
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDE9A-448H Active Recombinant Human Phosphodiesterase 9A, GST-tagged Insect Cell GST
Human PDE9A-1163H Recombinant Human PDE9A, His & GST tagged Insect Cell His/GST
Human PDE9A-1162H Recombinant Human PDE9A protein, His-tagged E.coli His
Human PDE9A-551H Recombinant Human PDE9A, His/GST-tagged Insect Cell His/GST
Human PDE9A-550H Recombinant Human PDE9A, His-tagged E.coli His
Human PDE9A-609HCL Recombinant Human PDE9A cell lysate Insect Cell N/A
Human PDE9A-043H Recombinant Human PDE9A Protein, His/GST-tagged Insect cell His/GST
Human PDE9A-921H Recombinant Human PDE9A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDE9A-3344H Recombinant Human PDE9A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDE9A-741H Recombinant Human PDE9A Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PDE9A-08H Recombinant Human PDE9A Protein, His/GST-tagged Insect Cell His/GST
Human PDE9A-6347H Recombinant Human PDE9A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDE9A-2568H Recombinant Human PDE9A Protein, His-tagged E.coli N-His
Mouse PDE9A-12566M Recombinant Mouse PDE9A Protein Mammalian Cell His
Mouse Pde9a-4753M Recombinant Mouse Pde9a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Pde9a-1493M Recombinant Mouse Pde9a protein, His-tagged E.coli His
Mouse PDE9A-6593M Recombinant Mouse PDE9A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PDE9A-6593M-B Recombinant Mouse PDE9A Protein Pre-coupled Magnetic Beads HEK293
Rat PDE9A-4336R Recombinant Rat PDE9A Protein Mammalian Cell His
Rat PDE9A-3996R Recombinant Rat PDE9A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PDE9A-3996R-B Recombinant Rat PDE9A Protein Pre-coupled Magnetic Beads HEK293
Kit-1849 PDE9A Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PDE9A involved in several pathways and played different roles in them. We selected most pathways PDE9A participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE9A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismCANT1B;PDE3A;PPAT;GUK1A;POLR3B;NT5C3A;AMPD3B;AK5;URAD

PDE9A has several biochemical functions, for example, 3,5-cyclic-GMP phosphodiesterase activity, 3,5-cyclic-nucleotide phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE9A itself. We selected most functions PDE9A had, and list some proteins which have the same functions with PDE9A. You can find most of the proteins on our site.

Function Related Protein
3,5-cyclic-GMP phosphodiesterase activityPDE11A;PDE9A;PDE6C;PDE6B;PDE5A;PDE6G;PDE10A;PDE6H;PDE6A
3,5-cyclic-nucleotide phosphodiesterase activityPDE11A;PDE8B;PDE5A;PDE9A;PDE4D;PDE5AB;PDE10A;PDE6D;PDE3B
metal ion bindingRPP21;SH3RF3;GDPD2;BTK;GALNT4;PRDM8B;ATP13A5;CAR5A;DNAJA3
protein bindingDTD2;SLC25A5;PACSIN2;CTSC;RBMY1F;NPDC1;NOP56;APLP2;CLTB

PDE9A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE9A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE9A.

TRIM32; C9orf106; BAG3; LMO2; CLK1

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