PDIA6
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Official Full Name
protein disulfide isomerase family A, member 6
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Overview
Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that;catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in;folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 (PubMed 7590364)). -
Synonyms
PDIA6; protein disulfide isomerase family A, member 6; protein disulfide isomerase associated 6 , thioredoxin domain containing 7 (protein disulfide isomerase) , TXNDC7; protein disulfide-isomerase A6; ERp5; P5; protein disulfide isomerase related protein; Endoplasmic reticulum protein 5; Protein disulfide isomerase A6; Protein disulfide isomerase associated 6; Protein disulfide isomerase family A member 6; Protein disulfide isomerase P5; Thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain containing protein 7; TXNDC7; ER protein 5; thioredoxin domain-containing protein 7; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- C
- His
- Flag
- GST
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
PDIA6 involved in several pathways and played different roles in them. We selected most pathways PDIA6 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDIA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| IRE1alpha activates chaperones | ADD1;CTDSP2;DDX11;DNAJB9;PREB;HDGF;KLHDC3;KDELR3;C19orf10 |
| Metabolism of proteins | PROCA;NAT8;DMBT1;ALG2;EEF1G;NSFA;GPR120;PFDN4;GRPEL2 |
| Protein processing in endoplasmic reticulum | ATF6;CALRL2;ERO1L;DERL1;ERP29;GANAB;HSPA1A;EIF2AK3;CALR3B |
| Unfolded Protein Response (UPR) | KDELR3;WIPI1;KLHDC3;SERP1;HYOU1;CTDSP2;DNAJB9;YY2;CXXC1 |
| XBP1(S) activates chaperone genes | CTDSP2;KDELR3;TPP1;ASNA1;HYOU1;WIPI1;SEC63;FKBP14;DNAJB9 |
PDIA6 has several biochemical functions, for example, protein binding, protein disulfide isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDIA6 itself. We selected most functions PDIA6 had, and list some proteins which have the same functions with PDIA6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RRS1;CLDN8;KIAA1109;TRAPPC6A;MT3;PPFIA1;SMR3B;GALNT2;CIB2 |
| protein disulfide isomerase activity | ITGB3;GLRX2;ERO1LB;PDIA5;ERP44;TMX1;TMX4;P4HB;PDIP5 |
PDIA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDIA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDIA6.
PRDX4; gag-pol; ganglioside_gm1; NME2; IKBKE; Bles03; TNFRSF14; PRKAB1; TRAF6; Dnajb9; CASP8; Dnajc10; Dnajb11; q81k28_bacan; q99ib8-pro_0000045599; ATP13A2; q9wmx2-pro_0000037550; gd3
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