PDS5A

  • Official Full Name

    PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

  • Overview

    The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    PDS5A;PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae);sister chromatid cohesion protein PDS5 homolog A;KIAA0648;PIG54;SCC 112;Cell proliferation inducing protein 54;KIAA0648.;sister chromatid cohesion protein 112;cell proliferation-inducing gene 54 protein;SCC112;SCC-112

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Rat
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
PDS5A-1628H Recombinant Human PDS5A, GST-tagged E.coli Human GST C-term-377aa
PDS5A-11226Z Recombinant Zebrafish PDS5A Mammalian Cells Zebrafish His
PDS5A-1952C Recombinant Chicken PDS5A Mammalian Cells Chicken His
PDS5A-4360R Recombinant Rat PDS5A Protein Mammalian Cells Rat His
PDS5A-1565HCL Recombinant Human PDS5A cell lysate Human Non
PDS5A-4020R Recombinant Rat PDS5A Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
PDS5A-4020R-B Recombinant Rat PDS5A Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    PDS5A involved in several pathways and played different roles in them. We selected most pathways PDS5A participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDS5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitotic Prometaphase CDCA8,CENPK,ZWILCH,SPDL1,NUF2,SMC4,NSL1,RCC2,CENPL,INCENP
    Establishment of Sister Chromatid Cohesion ESCO2,CDCA5,STAG2,WAPAL,PDS5B,STAG1,ESCO1
    Cell Cycle, Mitotic NCAPD2,NDEL1,MCM8,MAU2,TUBG1,CEP57,CDKN2C,RANGAP1B,CLASP1A,GORASP1
    Cell cycle TERF1,SYNE1,ACD,MCM3,CKS1B,CDK5RAP2,PMF1,MYCA,ZBTB17,FAM175A
    Cohesin Loading onto Chromatin STAG2,WAPAL,STAG1,NIPBLB,NIPBL,NIPBLA,MAU2,PDS5B
    M Phase ZWILCH,CTDNEP1A,SPDL1,SMC2,GORASP2,CNEP1R1,NCAPH2,SPC24,INCENP,ENSAA
    Mitotic Metaphase and Anaphase ZW10,PMF1,SKA1,WAPAL,CENPE,SGOL1,NDEL1,SPDL1,CENPP,ZWINT
    Mitotic Anaphase CDCA5,NDC80,NDEL1,CENPP,INCENP,CENPH,ERCC6L,NDEL1B,PMF1,DSN1

    Protein Function

    PDS5A has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDS5A itself. We selected most functions PDS5A had, and list some proteins which have the same functions with PDS5A. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TMEM66,NKX2,IFT43,Casp3,LMX1A,GTF3C6,MED15,HFE,TF,STAM2

    Interacting Protein

    PDS5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDS5A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDS5A.

    WAPAL;RAD21;SMC3;SMC1A

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