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PEF1

  • Official Full Name

    penta-EF-hand domain containing 1

  • Overview

    This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.
  • Synonyms

    PEF1; penta-EF-hand domain containing 1; peflin; PEF1A; ABP32; PEF; PEF protein with a long N terminal hydrophobic domain; Penta EF hand domain containing protein 1; penta-EF hand domain containing 1; PEF protein with a long N-terminal hydrophobic domain;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PEF1-1639H Recombinant Human PEF1, GST-tagged E.coli GST 117-284aa
Human PEFLIN-1555H Recombinant Human Penta-EF-hand Domain Containing 1, T7-tagged E.coli T7
Human PEF1-29168TH Recombinant Human PEF1 E.coli N/A
Human PEF1-3472H Recombinant Human PEF1, His-tagged E.coli His
Human PEF1-3308HCL Recombinant Human PEF1 293 Cell Lysate HEK293 N/A
Human PEF1-2105HFL Recombinant Full Length Human PEF1 Protein, C-Flag-tagged Mammalian cells Flag
Human PEF1-1645H-B Recombinant Human PEF1 Protein Pre-coupled Magnetic Beads HEK293
Human PEF1-1645H Recombinant Human PEF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pef1-4789M Recombinant Mouse Pef1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PEF1-4371R Recombinant Rat PEF1 Protein Mammalian Cell His
Rat PEF1-4031R Recombinant Rat PEF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PEF1-4031R-B Recombinant Rat PEF1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PEF1-1062Z Recombinant Zebrafish PEF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PEF1 Related Articles

PEF1 involved in several pathways and played different roles in them. We selected most pathways PEF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PEF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PEF1 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEF1 itself. We selected most functions PEF1 had, and list some proteins which have the same functions with PEF1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingEHD4;PCDH2AA1;ADAM8;TTN;CRB2;VIL1;PLA2G5;HPCAL4;CRNN
calcium-dependent cysteine-type endopeptidase activityCAPN9;SRI;PDCD6;PEF1;CAPNS1;CAPN1;CAPN3;CAPN1B;CAPN3A
poly(A) RNA bindingKIAA1324;LSM3;D19BWG1357E;DCD;YTHDC2;SAMSN1;MYBBP1A;SRSF9;G3BP1
protein bindingMSTN;ZRSR2;USP6;RTN4A;FAM206A;ERCC8;RAB41;VWF;CD1B
protein dimerization activityABCG1;HIF1AL2;ATOH7;MYCL1;MEF2CB;HES2;HER2;HER12;MESP1
protein heterodimerization activityUBA3;PRSS28;ADORA1;SMC3;PRMT8;KCNK3;SDCBP;ABTB2;BCL2A

PEF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEF1.

PDCD6; KLHL12; CALCOCO2; DAZAP2; CEP55

Partha, SK; Ravulapalli, R; et al. Crystal structure of calpain-3 penta-EF-hand (PEF) domain - a homodimerized PEF family member with calcium bound at the fifth EF-hand. FEBS JOURNAL 281:3138-3149(2014).
Osako, Y; Maemoto, Y; et al. Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction. FEBS JOURNAL 277:4412-4426(2010).
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