PI4K2A
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Official Full Name
phosphatidylinositol 4-kinase type 2 alpha
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Overview
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell;growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4;position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 (PubMed 11244087)). -
Synonyms
PI4K2A; phosphatidylinositol 4-kinase type 2 alpha; phosphatidylinositol 4-kinase type 2-alpha; DKFZP761G1923; PI4KII; PIK42A; phosphatidylinositol 4-kinase type II-alpha; phosphatidylinositol 4-kinase type II (PI4KII); RP11-548K23.6;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Sf9 Insect Cell
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- PI4K2A Related Articles
PI4K2A involved in several pathways and played different roles in them. We selected most pathways PI4K2A participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PI4K2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | MINPP1A;ITPKC;ITPK1;MTMR7A;PIP4K2AA;NUDT4;INPPL1A;PLCH1;PI4K2A |
| Metabolic pathways | ATP6V1G2;ADSSL;MTHFD1;AMY2A;NDUFB11;PPAP2C;ATP6V1BA;PLCD3;NAMPT |
| Phosphatidylinositol signaling system | ITPK1A;PIP5K1C;PLCB2;INPP4B;PLCD1B;MTMR7;PIK3CG;PLCB3;SYNJ1 |
PI4K2A has several biochemical functions, for example, 1-phosphatidylinositol 4-kinase activity, AP-3 adaptor complex binding, ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PI4K2A itself. We selected most functions PI4K2A had, and list some proteins which have the same functions with PI4K2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-phosphatidylinositol 4-kinase activity | PI4K2B;PI4KAB;PI4KB;PI4KAA;PI4K2A;PI4KA |
| AP-3 adaptor complex binding | PI4K2A;RAB38;RAB32 |
| ATP binding | PPP2R4;GK;PRKACB;STK3;SCYL1;STK26;Fert2;EHD3;EIF2AK4 |
| magnesium ion binding | HPGDS;NUDT5;PPA1A;PDXP;SIK2;PRPS1L1;TSSK1;CLYBL;IMPA2 |
| protein binding | ATP5G1;YTHDC1;FOXO3;WTAP;RIBC1;RTF1;RIMS2;LCE1B;CEP120 |
PI4K2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PI4K2A here. Most of them are supplied by our site. Hope this information will be useful for your research of PI4K2A.
ITCH; GABARAP; NOS3; RAD23A; CNOT1; PHF8
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