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PIP5KL1

  • Official Full Name

    phosphatidylinositol-4-phosphate 5-kinase-like 1

  • Overview

    PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I;PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 (PubMed;14701839)).
  • Synonyms

    PIP5KL1; phosphatidylinositol-4-phosphate 5-kinase-like 1; phosphatidylinositol-4-phosphate 5-kinase-like protein 1; bA203J24.5; MGC46424; EC 2.7.1.68; phosphatidylinositol 4 phosphate 5 kinase like 1; phosphatidylinositol phosphate kinase homolog; PI(4)P 5 kinase like protein 1; PIPKH; PtdIns(4)P 5 kinase like protein 1; PI(4)P 5-kinase-like protein 1; ptdIns(4)P-5-kinase-like protein 1; RP11-203J24.5;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PIP5KL1-5675HF Active Recombinant Full Length Human PIP5KL1 Protein, GST-tagged Insect (sf21) GST 1-394(end)
Human PIP5KL1-3171HCL Recombinant Human PIP5KL1 293 Cell Lysate HEK293 N/A
Mouse PIP5KL1-12831M Recombinant Mouse PIP5KL1 Protein Mammalian Cell His
Mouse PIP5KL1-6758M Recombinant Mouse PIP5KL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PIP5KL1-6758M-B Recombinant Mouse PIP5KL1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PIP5KL1 involved in several pathways and played different roles in them. We selected most pathways PIP5KL1 participated on our site, such as 3-phosphoinositide biosynthesis, D-myo-inositol (1,4,5)-trisphosphate biosynthesis, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIP5KL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
3-phosphoinositide biosynthesisPIK3R6;CDIPT;FIG4;PIP5KL1
D-myo-inositol (1,4,5)-trisphosphate biosynthesisPLCD3;PIP5KL1;CDIPT
EndocytosisSTAMBPA;EPN2;PARD6A;SMAP2;CLINT1A;SH3GL1;PARD6B;ERBB3A;MHC1UEA
Inositol phosphate metabolismMTMR1;INPP4A;PIP5K1BA;SYNJ2;PIP5K2;MINPP1;ITPKC;MTMR7;MTMR8
Metabolic pathwaysAGPAT4;SAT2;PNAT10;PAFAH1B1B;TCIRG1;CHPF;MPI;UGT1A1;ARG2
Regulation of Actin CytoskeletonPIK3CB;ARHGEF1;BDKRB2;MYL1;FGFR1A;ITGB1A;FGF5;RHOAB;RAC3B
superpathway of inositol phosphate compoundsIP6K3;PIP5KL1

PIP5KL1 has several biochemical functions, for example, 1-phosphatidylinositol-4-phosphate 5-kinase activity, ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIP5KL1 itself. We selected most functions PIP5KL1 had, and list some proteins which have the same functions with PIP5KL1. You can find most of the proteins on our site.

Function Related Protein
1-phosphatidylinositol-4-phosphate 5-kinase activityPIP4K2A;PIP5K1B;PIP5K1C;PIP5KL1;PIP4K2B;PIKFYVE;PIP4K2C;PIP5K1A
ATP bindingDGKE;GRK7A;PIP4K2C;HARS2;MVD;ZAP70;SIK3;ACTB2;FES

PIP5KL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIP5KL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIP5KL1.

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