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PJA2

  • Official Full Name

    praja ring finger 2

  • Overview

    E3 ubiquitin-protein ligase Praja2 is an enzyme that in humans is encoded by the PJA2 gene.
  • Synonyms

    PJA2; praja ring finger 2; E3 ubiquitin-protein ligase Praja-2; E3 ubiquitin protein ligase Praja2; KIAA0438; Neurodap 1; Neurodap1; PJA 2; PJA2_HUMAN; Praja 2; Praja 2 RING H2 motif containing; Praja2; RING finger protein 131; RNF 131; RNF131; OTTHUMP00000158944; praja 2, RING-H2 motif containing;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PJA2-3159HCL Recombinant Human PJA2 293 Cell Lysate HEK293 N/A
Mouse PJA2-12856M Recombinant Mouse PJA2 Protein Mammalian Cell His
Mouse PJA2-6776M Recombinant Mouse PJA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PJA2-6776M-B Recombinant Mouse PJA2 Protein Pre-coupled Magnetic Beads HEK293
Rat PJA2-4479R Recombinant Rat PJA2 Protein Mammalian Cell His
Rat PJA2-4139R-B Recombinant Rat PJA2 Protein Pre-coupled Magnetic Beads HEK293
Rat PJA2-4139R Recombinant Rat PJA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PJA2 involved in several pathways and played different roles in them. We selected most pathways PJA2 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PJA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemKIF2B;UBR1;SH3RF1;RNF19B;RNF138;IGLC2;HECTD3;CTS7;DYNLL2
Antigen processing: Ubiquitination &ampLRR1;UBE2J2;ATG7;SH3RF1;DTX3L;SPSB4;RNF4;ASB6;KLHL20
Proteasome degradationASB18;RNF34;LRSAM1;UCHL3;ASB14;UBE2F;ASB11;VPRBP;LTN1
Class I MHC mediated antigen processing &ampUBE2E3;SH3RF1;RNF4;ASB18;UBE2L6;ASB9;RNF111;RNF138;GAN
presentationUBE2L6;UFL1;SPSB4;CYBA;ASB7;RNF41;LRSAM1;SEC23A;FBXO17
Immune SystemASB10;POLR3G;PANX1A;CTSE;PRLRB;WWP1;RNF182;RCA2.1;CLEC4A

PJA2 has several biochemical functions, for example, ligase activity, protein kinase A catalytic subunit binding, protein kinase A regulatory subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PJA2 itself. We selected most functions PJA2 had, and list some proteins which have the same functions with PJA2. You can find most of the proteins on our site.

Function Related Protein
ligase activityRNF133;NEDD4L;HERC4;HERC2;HERC5;MYLIP;TRAF2;GATB;PIAS3
protein kinase A catalytic subunit bindingGSK3A;PRKAR1A;PRKAR2B;EZR;KCNQ1;PRKAR1B;GSK3B;PKIA;PJA2
protein kinase A regulatory subunit bindingRYR2;AKAP5;C2orf88;PRKACA;EZR;AKAP8;ARFGEF1;ARFGEF2;KCNQ1
ubiquitin protein ligase activityCDC42;ITCHA;UBE3C;UBE2N;ARIH1L;RNF115;RNF4;PARK2;ANKIB1A
ubiquitin-protein transferase activityFBXO9;TRIM21;TRAF4B;RFWD3;CBL;FBXO11;ZYG11;BIRC3;RNF141
zinc ion bindingDTNBB;NR5A1A;NRAP;ZCCHC2;MMP13;WHSC1L1;CPD;C6AST1;UQCRC2

PJA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PJA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PJA2.

PRKAR2A; USP46; UBE2L6; UBE2D1; UBE2D3; UBE2N; UBE2D2; q81vw1_bacan; fabF; UBE2W; UBE2D4; UBE2J1; UBXN7; UBXN1; FAF2; FAF1

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