Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

PKNOX2

Official Full Name

PBX/knotted 1 homeobox 2
Overview

Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and;play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid;loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2;within the homeodomain (Imoto et al., 2001 (PubMed 11549286)).
Synonyms

PKNOX2; PBX/knotted 1 homeobox 2; homeobox protein PKNOX2; FLJ13074; Homeobox protein PREP 2; PBX/knotted homeobox 2; PREP2; OTTHUMP00000231418; OTTHUMP00000231419; OTTHUMP00000231420; homeobox protein PREP-2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PKNOX2-1747H	Recombinant Human PKNOX2, GST-tagged	E.coli	GST	C-122aa	$319 / 25ug
Human	PKNOX2-1364HCL	Recombinant Human PKNOX2 cell lysate		N/A		Inquiry
Mouse	PKNOX2-12877M	Recombinant Mouse PKNOX2 Protein	Mammalian Cell	His		Inquiry
Mouse	PKNOX2-6790M	Recombinant Mouse PKNOX2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PKNOX2-6790M-B	Recombinant Mouse PKNOX2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PKNOX2-9461Z	Recombinant Zebrafish PKNOX2	Mammalian Cell	His		Inquiry
Chicken	PKNOX2-5799C	Recombinant Chicken PKNOX2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PKNOX2 involved in several pathways and played different roles in them. We selected most pathways PKNOX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PKNOX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PKNOX2 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, actin filament binding, actin monomer binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PKNOX2 itself. We selected most functions PKNOX2 had, and list some proteins which have the same functions with PKNOX2. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II regulatory region sequence-specific DNA binding	TFAP2D;NR1I3;H2AFY2;PURB;ARID5B;CREB3L4;SP5;BCL6AB;LYL1
actin filament binding	EZR;SCIN;TMOD1;BLOC1S6;CORO2B;CORO1CA;TAGLN3B;SMYHC2;ARPC1A
actin monomer binding	PFN2;TWF2;MKL1B;COBLL1;PKNOX2;MYL3;MYL4;ABL2;PRKCE

PKNOX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKNOX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKNOX2.

FOS