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PLEKHA3

  • Official Full Name

    pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3

  • Overview

    Binds specifically to phosphatidylinositol-4-phosphate (PtdIns4P), but not to other phosphoinositides.
  • Synonyms

    PLEKHA3; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3; pleckstrin homology domain-containing family A member 3; FAPP1; four phosphate adaptor protein 1; FAPP 1; FAPP-1; FLJ20067; PH domain-containing family A member 3; Phosphatidylinositol-four-phosphate adapter protein 1; Phosphoinositol 4 phosphate adaptor protein 1; Phosphoinositol 4-phosphate adapter protein 1; PKHA3_HUMAN; Pleckstrin homology domain containing family A (phosphoinositide binding specific) member 3; Pleckstrin homology domain containing family A member 3; PLEKHA 3; OTTHUMP00000205697; four-phosphate-adaptor protein 1; p;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLEKHA3-1776H Recombinant Human PLEKHA3, GST-tagged E.coli GST 1-300aa
Human PLEKHA3-3117HCL Recombinant Human PLEKHA3 293 Cell Lysate HEK293 N/A
Human PLEKHA3-4551H Recombinant Human PLEKHA3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Plekha3-4926M Recombinant Mouse Plekha3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish PLEKHA3-11423Z Recombinant Zebrafish PLEKHA3 Mammalian Cell His
Chicken PLEKHA3-2910C Recombinant Chicken PLEKHA3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PLEKHA3 Related Articles

PLEKHA3 involved in several pathways and played different roles in them. We selected most pathways PLEKHA3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEKHA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PLEKHA3 has several biochemical functions, for example, 1-phosphatidylinositol binding, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHA3 itself. We selected most functions PLEKHA3 had, and list some proteins which have the same functions with PLEKHA3. You can find most of the proteins on our site.

Function Related Protein
1-phosphatidylinositol bindingSNX10;ZFYVE16;PICALMA;SCARB1;EEA1;FRMPD2;PLEKHA2;PICALM;PLEKHA4
phospholipid bindingNSMAF;BAD;SNCA;SPTB;STAP1;ABCA1;ARHGAP44;NUP35;SEC14L2

PLEKHA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHA3.

CSDE1; Csde1

Liu, JM; Fukuda, K; et al. Structural Basis of Phosphoinositide Binding to Kindlin-2 Protein Pleckstrin Homology Domain in Regulating Integrin Activation. JOURNAL OF BIOLOGICAL CHEMISTRY 286:43334-43342(2011).
Ooms, LM; Horan, KA; et al. The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease. BIOCHEMICAL JOURNAL 419:29-49(2009).
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