PLEKHG2
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Official Full Name
pleckstrin homology domain containing, family G (with RhoGef domain) member 2 -
Synonyms
PLEKHG2;pleckstrin homology domain containing, family G (with RhoGef domain) member 2;pleckstrin homology domain-containing family G member 2;ARHGEF42;CLG;FLJ00018;FLJ22458;Pleckstrin homology domain containing family G member 2;PH domain-containing family G member 2;common-site lymphoma/leukemia guanine nucleotide exchange factor
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PLEKHG2-2747H | Recombinant Human PLEKHG2 protein, His-tagged | E.coli | Human | His | 284-368 aa | |
| PLEKHG2-1375HCL | Recombinant Human PLEKHG2 cell lysate | Human | Non |
|
Involved Pathway
PLEKHG2 involved in several pathways and played different roles in them. We selected most pathways PLEKHG2 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE,G alpha (12/13) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEKHG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by Rho GTPases | ABI1A,ARHGAP29,RHPN2,PRC1,NOXO1,TAX1BP3,LIN7B,RHOJ,ARHGAP10,IQGAP3 |
| Signaling by GPCR | GHRH,ANXA1B,PYYA,CCL19A.2,GPR55A,UTS2D,OR52J3,OR7D2,RCA2.1,MLN |
| Rho GTPase cycle | MCF2L,FAM13A,ARAP2,TAGAPA,NET1,ARHGAP40,ARHGAP32,RHOT2,CHN2,ARHGAP33 |
| Signal Transduction | NOG1,MOB1BA,TNKS2,CXCL11.8,ABCA4A,ARHGAP18,RSPO4,EMR1,RGS14,ARHGAP29B |
| GPCR downstream signaling | PIK3R6,VIP2,OXTRL,OPN4.1,PTHLH,SSTR4,HCRT,GCGA,SOUL3,FPR-RS3 |
| G alpha (12/13) signalling events | ARHGEF16,FGD2,ARHGEF1A,MCF2L,RHOAE,ARHGEF18A,RHOC,ABR,FGD4,RHOB |
| NRAGE signals death through JNK | OBSCN,FGD2,NET1,ARHGEF17,DCLRE1B,ECT2,ARHGEF18,ARHGEF1A,FGD4,AATF |
| Cell death signalling via NRAGE, NRIF and NADE | ARHGEF9,ARHGEF16,KALRN,ARHGEF18A,AATF,ARHGEF18,ITSN1,CASP2,TIAM2,FGD2 |
Protein Function
PLEKHG2 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHG2 itself. We selected most functions PLEKHG2 had, and list some proteins which have the same functions with PLEKHG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rho guanyl-nucleotide exchange factor activity | FGD4,C3A.1,FGD4A,PLEKHG6,TRIO,TRIOA,DNMBP,FARP2,ITSN1,PLEKHG3 |
| protein binding | FGA,APBB1,EGR1,SKA1,DCAF11,CD27,DYNLT3,PSMG1,PENK,HSPB1 |
Interacting Protein
PLEKHG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHG2.
dxs;mexB;inhA
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