Pole4
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Official Full Name
polymerase (DNA-directed), epsilon 4, accessory subunit
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POLE4-1831H | Recombinant Human POLE4, His-tagged | E.coli | Human | His | 1-117aa | |
| POLE4-13077M | Recombinant Mouse POLE4 Protein | Mammalian Cells | Mouse | His |
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| POLE4-3509R | Recombinant Rhesus monkey POLE4 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| POLE4-3048HCL | Recombinant Human POLE4 293 Cell Lysate | HEK293 | Human | Non |
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| POLE4-3327R | Recombinant Rhesus Macaque POLE4 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| POLE4-3327R-B | Recombinant Rhesus Macaque POLE4 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| POLE4-6909M | Recombinant Mouse POLE4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| POLE4-6909M-B | Recombinant Mouse POLE4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Pole4 involved in several pathways and played different roles in them. We selected most pathways Pole4 participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pole4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nucleotide Excision Repair | ERCC2,RFC1,RAD23AB,KIAA1530,ACTR5,RFC5,YY1,INO80,INO80C,XPC |
| Metabolic pathways | PIGS,EXTL1,LPCAT1,POLE3,UGT2B15,PCYT1AB,GCLC,DPAGT1,BAAT,DHCR7 |
| Purine metabolism | GUCY1B3,ENPP1,GUCY1A3,PDE10A,POLR2L,PRPS1B,NME1,ENTPD2,NME6,GMPR2 |
| Pyrimidine metabolism | ENTPD8,NT5C2A,PNP,POLR2D,POLR3GL,POLR1B,ENTPD6,UPB1,PNP6,POLR2B |
| HTLV-I infection | TBPL1,FDPS,EP300,TLN1,HLA-DRA,HLA-G,XBP1,FOS,SMAD3,HRAS |
| Base excision repair | PARP4,POLE2,HMGB1B,LIG1,xthA,POLD3,APEX2,NEIL3,TDG.1,HMGB1A |
| DNA Replication | RPA4,GMNN,MCM3,SSBP1,PRIM1,RFC3,RNASEH2A,MCM3L,MCM5,CDT1 |
Protein Function
Pole4 has several biochemical functions, for example, DNA binding,DNA-directed DNA polymerase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Pole4 itself. We selected most functions Pole4 had, and list some proteins which have the same functions with Pole4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | DMRT1,IRAK1,CHRNB2,UGT1A1,SEPHS1,DRAP1,SOX17,ADORA2A,HOMER2,HIST1H2AA |
| protein binding | SERINC1,CLIP1,APOO,AIM2,PAK1IP1,PXN,SUMO2,FERD3L,MLLT6,CCT8 |
| DNA-directed DNA polymerase activity | CHRAC1,POLL,POLG2,POLA2,MYBBP1A,POLD2,POLN,POLD4,POLA1,POLI |
| DNA binding | THAP11,ZNF12,PCXB,HOXC5A,ZFP641,HMGB1B,HIST1H2BH,HIST1H4J,NR5A2,BEND5 |
Interacting Protein
Pole4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pole4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Pole4.
NFYB;POLE3;ORF;HSPA13;UBE3A;POLE2;POLE
Resources
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References
- Abdelmohsen, K; Srikantan, S; et al. Growth Inhibition by miR-519 via Multiple p21-Inducing Pathways. MOLECULAR AND CELLULAR BIOLOGY 32:2530-2548(2012).
- Park, IJ; Lee, BH; et al. Mixed Micellization of Sodium Dodecylbenzene Sulfonate with Polyoxyethylene Lauryl Ether Surfactants (POLE4 and POLE23) in n-Butanol Aqueous Solution. JOURNAL OF SURFACTANTS AND DETERGENTS 15:41-46(2012).
