POU2F1

  • Official Full Name

    POU class 2 homeobox 1
  • Overview

    The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 (PubMed 8314572)). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.
  • Synonyms

    POU2F1;POU class 2 homeobox 1;OTF1, POU domain class 2, transcription factor 1;POU domain, class 2, transcription factor 1;OCT1;NF-A1;OTF-1;oct-1;octamer-binding protein 1;Octamer-binding transcription factor-1;octamer-binding transcription factor 1;OTF1;oct-1B;FLJ42836

Recombinant Proteins

  • Mouse
  • Rat
  • Chicken
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • T7
  • GST
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
POU2F1-13138M Recombinant Mouse POU2F1 Protein Mammalian Cells Mouse His
POU2F1-4582R Recombinant Rat POU2F1 Protein Mammalian Cells Rat His
POU2F1-7021C Recombinant Chicken POU2F1 Mammalian Cells Chicken His
POU2F1-7110H Recombinant Human POU2F1 protein, His & T7-tagged E.coli Human His&T7 Asn413~Leu671
Pou2f1-7111M Recombinant Mouse Pou2f1 protein, His & GST-tagged E.coli Mouse GST&His Ala128~Leu391
POU2F1-3003HCL Recombinant Human POU2F1 293 Cell Lysate HEK293 Human Non
POU2F1-1524H Recombinant Human POU2F1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
POU2F1-4242R Recombinant Rat POU2F1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
POU2F1-4242R-B Recombinant Rat POU2F1 Protein Pre-coupled Magnetic Beads HEK293 Rat
POU2F1-4960H Recombinant Human POU2F1 Protein (Ala413-Val671), N-His tagged E.coli Human His Ala413-Val671
Pou2f1-5018M Recombinant Mouse Pou2f1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
POU2F1-6950M Recombinant Mouse POU2F1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
POU2F1-6950M-B Recombinant Mouse POU2F1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    POU2F1 involved in several pathways and played different roles in them. We selected most pathways POU2F1 participated on our site, such as ATF-2 transcription factor network,Calcineurin-regulated NFAT-dependent transcription in lymphocytes,Calcium signaling in the CD4+ TCR pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with POU2F1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcineurin-regulated NFAT-dependent transcription in lymphocytes EGR4,IKZF1,EGR2,CDK4,IRF4,CTLA4,EGR3,CSF2,BATF3,EGR1
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription CHD4,GATAD2AB,MTERF,NFIX,BRF1B,CRCP,SNAPC1B,CHD4A,PTRF,SNAPC5
    Glucocorticoid receptor regulatory network SMARCD1,SMARCA4,BGLAP,CSN2,EGR1,KRT17,KRT5,KRT14,NR1I3,SMARCC2
    Calcium signaling in the CD4+ TCR pathway FKBP1A,JUNB,CHP,BATF3,RCAN2,RCAN1,AKAP5,CSF2
    RNA Polymerase III Abortive And Retractive Initiation BRF1,GTF3C4,SNAPC2,GTF3C5,BRF2,NFIA,SNAPC1,GTF3C2,SNAPC4,NFIX
    FOXA1 transcription factor network CC10,CEBPB,DSCAM,NR2F2,NFIC,TFF1,NFIA,CYP2C18,NRIP1,NFIB
    Gene Expression ZNF434,EHMT2,CLNS1A,ZNF302,ZNF180,DARS,RPP30,SAP130,HNRNPL,C22orf28
    ATF-2 transcription factor network DDIT3,CDK4,KAT5,GADD45A,JUND,JDP2,DUSP5,HRK,DUSP1,RUVBL2

    Protein Function

    POU2F1 has several biochemical functions, for example, chromatin binding,protein binding,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU2F1 itself. We selected most functions POU2F1 had, and list some proteins which have the same functions with POU2F1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SEC61B,MST1R,IGFL1,ATP6V1H,PPP1R15B,NR1I2,EDAR,MYO6,SPA17,GYG1
    transcription factor activity, sequence-specific DNA binding OTX1A,PHTF1,FOXP1A,HES1,FOXA1,ZFP1,ZIC1,MYCLA,TCEAL1,HES6
    chromatin binding BRD3,CALCOCO1,HDAC4,CDCA5,SOX15,C10orf119,BAP1,WACA,NCAPD2,SOX9
    transcription regulatory region sequence-specific DNA binding NR5A5,NFE2L1A,MKL1,NFE2L2,ATF3,TFAP2A,CRY2,MEF2CA,NR5A1,NONO
    sequence-specific DNA binding TCF7L1B,RARAA,THRA,E2F5,HOXB2,USF1,HNF1B,MEOX2B,HOXB9A,HSF5
    receptor binding C5,A2M,GRIN2A,GCG,FGF20B,ACOT8,NCK1,LGI1,SMARCD3,CRH

    Interacting Protein

    POU2F1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU2F1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU2F1.

    SP1;SP4;POGZ;PLK3;TEAD1;rta_ebvb9

    Resources

    References

    • Vieweg, M; Dvorakova-Hortova, K; et al. Methylation analysis of histone H4K12ac-associated promoters in sperm of healthy donors and subfertile patients. CLINICAL EPIGENETICS 7:-(2015).
    • Balint, BL; Gabor, P; et al. Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line. IMMUNOBIOLOGY 210:141-152(2005).

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